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Gene · 1363

CPE: carboxypeptidase E

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CPE: carboxypeptidase E. Genes, record 1363. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1363

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Gene

Symbol
CPE
HGNC
Name
carboxypeptidase E
HGNC
NCBI Gene ID
1363
NCBI Gene
HGNC ID
HGNC:2303
HGNC
Ensembl
ENSG00000109472
NCBI Gene
Aliases
BDVS, CPH, IDDHH
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P16870Carboxypeptidase E4760Ensembl, GeneID, HGNC

Source UniProt

Patents82

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11578P16870Espacenet
JP 2026004568 A2026-01-1440061P16870Espacenet
EP 4650780 A22025-11-1911994P16870Espacenet
JP 2025147176 A2025-10-063439P16870Espacenet
WO 2025199149 A12025-09-256020P16870Espacenet
JP 2025529142 A2025-09-045990P16870Espacenet
US 12371689 B22025-07-295990P16870Espacenet
JP 2025517970 A2025-06-1211994P16870Espacenet
JP 2025062604 A2025-04-1411859P16870Espacenet
JP 2025032204 A2025-03-1126735P16870Espacenet

1 to 10 of 82

See all 82 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,436

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCPE papersNewest fiscal year
ZIAHD000056Neuropeptides and Carboxypeptidase E/ Neurotrophic Factor-alpha1 in Neural and Cognitive Functions372025
P30CA013330Cancer Center Support Grant92025
P30DK020572Michigan Diabetes Research Center (MDRC)82025
P30DK026687New York Obesity Research Center52025
P30DK097512Indiana Diabetes Research Center52025
R35GM138368Structure and Assembly of Membrane Proteins at Tight Junctions52025
ZICHD008874NICHD Microscopy and Imaging Core Facility52025
I01BX001733Regulation of calcium homeostasis in the pancreatic beta cell42025
P30CA008748Cancer Center Support Grant42025
P30DK020595Diabetes Research and Training Center42025

1 to 10 of 1,436Source NIH's project files

See all 1,436 nih grants

Papers2,249

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Bimetallic Zn/Cu Metal-Organic Framework (MOF)/ Two-Dimensional i-MBene Hybrid Electrodes for Enhanced Supercapacitor Performance.Small202642808812PubTator, text miningPubMed
Electrochemical determination of terbutaline using a SnO2 nanoparticle-modified carbon paste electrode.Turk J Chem202642683130PubTator, text miningPubMed
Application of Serum CA125, HE4, ROMA, and CPH-I in the Preoperative Differentiation of Ovarian Tumors: A Diagnostic Accuracy Study.J Clin Lab Anal202642578276PubTator, text miningPubMed
miR487a-3p and miR6855-3p Facilitate Macrophage Proinflammatory Polarization and Lipid Accumulation in Atherosclerosis.Arterioscler Thromb Vasc Biol202642488944PubTator, text miningPubMed
A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour-targeting function.Br J Pharmacol202642425537PubTator, text miningPubMed
Fungal oxyluciferin is recycled by caffeylpyruvate hydrolases.FEBS J202642159390PubTator, text miningPubMed
Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway.FEBS J202642157621PubTator, text miningPubMed
LEMONmethyl-seq: Targeted long-read DNA methylation profiling reveals dynamics of CRISPR epigenome editing and endogenous DNA methylation patterns.bioRxiv202642124676PubTator, text miningPubMed
Stepwise Increase of Carboxypeptidase E and Altered ALDH1A1 Expression During Cervical Carcinogenesis: A Retrospective Immunohistochemical Study.Int J Gynecol Pathol202642101847PubTator, text miningPubMed
Integrative In Silico and FFPE Tissue Analyses Elucidate Upregulated Genes in Colorectal Cancer Enriched for Tie2-Expressing Macrophages/Monocytes.Int J Mol Sci202642074283PubTator, text miningPubMed

1 to 10 of 2,249

See all 2,249 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1363

GET https://conductscience.org/api/genes/v1/1363/patents?page=2