Gene · 1365
CLDN3: claudin 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CLDN3: claudin 3. Genes, record 1365. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1365
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15551 | Claudin-3 | 220 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents157
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026126292 A | 2026-08-04 | 5 | O15551 | Espacenet |
| JP 2026126293 A | 2026-08-04 | 5 | O15551 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41658 | O15551 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 988 | O15551 | Espacenet |
| US 12403202 B2 | 2025-09-02 | 5 | O15551 | Espacenet |
| WO 2025177214 A1 | 2025-08-28 | 22 | O15551 | Espacenet |
| JP 2025122026 A | 2025-08-20 | 5 | O15551 | Espacenet |
| JP 2025122027 A | 2025-08-20 | 5 | O15551 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 988 | O15551 | Espacenet |
| JP 2025521567 A | 2025-07-10 | 4 | O15551 | Espacenet |
1 to 10 of 157
See all 157 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,332
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CLDN3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 9 | 2025 |
| P50CA058223 | SPORE in Breast Cancer | 8 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016359 | Cancer Center Support Grant | 6 | 2025 |
| R01DK057819 | Intestinal Mucosal Growth in Health and Surgical Diseases | 6 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 6 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 5 | 2025 |
| I01BX000332 | Posttranscriptional Control of Gut Mucosal Defense and Homeostasis | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,332Source NIH's project files
See all 1,332 nih grantsPapers2,896
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| TGM2 Activates the ERK Signaling Pathway to Disrupt Intestinal Barrier Function and Aggravate Colitis. | Front Biosci (Landmark Ed) | 2026 | 42811980 | PubTator, text mining | PubMed |
| Conserved Epithelial Remodeling Programs Underlie Pediatric Juvenile Colorectal Polyps Associated with Allergic Sensitization. | Int J Mol Sci | 2026 | 42737845 | PubTator, text mining | PubMed |
| Nicastrin Regulates Cutaneous Squamous Cell Carcinoma Progression Through the MAPK/ERK Signalling. | Exp Dermatol | 2026 | 42712002 | PubTator, text mining | PubMed |
| Probiotics and intestinal permeability in adults with metabolic dysfunction-associated steatohepatitis: A secondary analysis of a randomized clinical trial. | JPEN J Parenter Enteral Nutr | 2026 | 42701874 | PubTator, text mining | PubMed |
| Tight junction-related proteins in the upper reproductive tract luminal and glandular epithelial cells are regionally regulated across the estrous cycle. | Front Endocrinol (Lausanne) | 2026 | 42676457 | PubTator, text mining | PubMed |
| CK8/18 and Claudin Profile of Female Breast Cancers from Botswana. | Breast Cancer (Auckl) | 2026 | 42668738 | PubTator, text mining | PubMed |
| Breaking the Barrier: Pro-inflammatory Stool from Infants with CHD Triggers Barrier Dysfunction within Intestinal Organoids. | Res Sq | 2026 | 42619927 | PubTator, text mining | PubMed |
| Proteomic Profiling Identifies CLDN3 as a Tumor-Selective Therapeutic Target in Small Cell Lung Cancer. | bioRxiv | 2026 | 42619739 | PubTator, text mining | PubMed |
| Single-Cell Profiling Identifies the SPDEF/GAS5 Axis as a Potential Driver of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer. | Cureus | 2026 | 42528776 | PubTator, text mining | PubMed |
| Impact of Deoxynivalenol, Cytokines, and Particulate Matter on Human Trophoblast Cells. | Int J Mol Sci | 2026 | 42511775 | PubTator, text mining | PubMed |
1 to 10 of 2,896
See all 2,896 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1365
GET https://conductscience.org/api/genes/v1/1365/patents?page=2