ConductScience.org, home

Gene · 1366

CLDN7: claudin 7

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. CLDN7: claudin 7. Genes, record 1366. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1366

On this page

Gene

Symbol
CLDN7
HGNC
Name
claudin 7
HGNC
NCBI Gene ID
1366
NCBI Gene
HGNC ID
HGNC:2049
HGNC
Ensembl
ENSG00000181885
NCBI Gene
Aliases
CEPTRL2, CLDN-7, CPETRL2, Hs.84359, claudin-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95471Claudin-72110Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025147176 A2025-10-062966O95471Espacenet
JP 2025147176 A2025-10-062967O95471Espacenet
JP 2025529142 A2025-09-04992O95471Espacenet
JP 2025529142 A2025-09-045894O95471Espacenet
US 12371689 B22025-07-295894O95471Espacenet
US 12371689 B22025-07-29992O95471Espacenet
JP 2025028160 A2025-02-282966O95471Espacenet
JP 2025028160 A2025-02-282967O95471Espacenet
KR 1020250010750 A2025-01-212966O95471Espacenet
KR 1020250010750 A2025-01-212967O95471Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,094

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCLDN7 papersNewest fiscal year
P30CA016672Cancer Center Support Grant302025
P30DK058404Molecular and Cellular Basis for Digestive Diseases142025
P30CA068485Cancer Center Support Grant122025
P50CA058223SPORE in Breast Cancer112025
P30CA016086Cancer Center Support Grant52025
R01CA148761Therapeutic Targeting of Breast Cancer Tumor Initiating Cells52025
P30CA006927Comprehensive Cancer Center Program at Fox Chase42025
P30CA008748Cancer Center Support Grant42025
P30ES010126UNC Center for Environmental Health and Susceptibility42025
P30CA006973Regional Oncology Research Center32025

1 to 10 of 1,094Source NIH's project files

See all 1,094 nih grants

Papers1,866

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Phosphoproteomic Insights into TRPV4-AMPK Signaling Axis and Barrier Regulation in the Choroid Plexus Epithelium.Int J Mol Sci202642794733PubTator, text miningPubMed
CK8/18 and Claudin Profile of Female Breast Cancers from Botswana.Breast Cancer (Auckl)202642668738PubTator, text miningPubMed
Phosphoproteomic Insights into TRPV4-AMPK Signaling Axis in the Choroid Plexus Epithelium: Implications for Therapeutic Targeting in Hydrocephalus.bioRxiv202642523348PubTator, text miningPubMed
Matriptase proteolysis selectively drives disassembly and internalization of the claudin-7 complex while preserving E-cadherin.Hum Cell202642440028PubTator, text miningPubMed
Immunohistochemical profiling of ampullary carcinoma: Molecular subtypes, prognostic markers, and the role of Claudin-18.Virchows Arch202642406030PubTator, text miningPubMed
Modeling Human Hypertrophic Scars with Induced Pluripotent Stem-Cell-Derived Scar Organoids Versus Skin Organoids.Cells202642274563PubTator, text miningPubMed
Simulated Mars Gravity Impairs Intestinal Epithelial Barrier Integrity via Selective Modulation of Tight Junction Components.Biomolecules202642194087PubTator, text miningPubMed
Identification of RPL4 as a biomarker associated with disulfidptosis and arachidonic acid metabolism in breast cancer.Discov Oncol202642096008PubTator, text miningPubMed
Knocking down CLDN7 enhanced the effect of cisplatin in OC cells by regulating mitophagy.J Ovarian Res202642057112PubTator, text miningPubMed
TROP2/claudin program mediates immune exclusion to impede checkpoint blockade in breast cancer.J Immunother Cancer202641932810PubTator, text miningPubMed

1 to 10 of 1,866

See all 1,866 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1366

GET https://conductscience.org/api/genes/v1/1366/patents?page=2