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Gene · 1375

CPT1B: carnitine palmitoyltransferase 1B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CPT1B: carnitine palmitoyltransferase 1B. Genes, record 1375. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1375

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Gene

Symbol
CPT1B
HGNC
Name
carnitine palmitoyltransferase 1B
HGNC
NCBI Gene ID
1375
NCBI Gene
HGNC ID
HGNC:2329
HGNC
Ensembl
ENSG00000205560
NCBI Gene
Aliases
CPT1-M, CPT1M, CPTI, CPTI-M, M-CPT1, MCCPT1, MCPT1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92523Carnitine O-palmitoyltransferase 1, muscle isoform7720Ensembl, GeneID, HGNC

Source UniProt

Patents127

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440105Q92523Espacenet
JP 2026004568 A2026-01-1440106Q92523Espacenet
JP 2026004568 A2026-01-1440107Q92523Espacenet
JP 2026004568 A2026-01-1440108Q92523Espacenet
EP 4641201 A22025-10-294385Q92523Espacenet
JP 2025529142 A2025-09-041107Q92523Espacenet
US 12371689 B22025-07-291107Q92523Espacenet
JP 2025517969 A2025-06-124385Q92523Espacenet
JP 2025062604 A2025-04-1411993Q92523Espacenet
JP 2025062604 A2025-04-1411994Q92523Espacenet

1 to 10 of 127

See all 127 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
PERHEXILINECHEMBL75880Carnitine O-palmitoyltransferase 1, muscle isoform inhibitorINHIBITORChEMBL
PERHEXILINE MALEATECHEMBL1334033Carnitine O-palmitoyltransferase 1, muscle isoform inhibitorINHIBITORChEMBL

Trials7

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04426578PERHEXILINEPHASE2ClinicalTrials.gov
NCT02862600PERHEXILINEPHASE22017-08-31ClinicalTrials.gov
NCT02431221PERHEXILINE MALEATEPHASE3ClinicalTrials.gov
NCT00989508PERHEXILINEPHASE2/PHASE3ClinicalTrials.gov
NCT00841139PERHEXILINEPHASE2ClinicalTrials.gov
NCT00628056PERHEXILINEPHASE1/PHASE2ClinicalTrials.gov
NCT00500552PERHEXILINEPHASE2ClinicalTrials.gov

NIH grants1,197

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCPT1B papersNewest fiscal year
P30DK072476Pennington/Louisiana NORC72025
U54GM104940Louisiana Clinical and Translational Science Center72025
P30DK020579Diabetes Research Center52025
P30DK056336UAB Nutrition Obesity Research Center (NORC)52025
P30DK056341Washington University Nutrition Obesity Research Center52025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant42025
P30DK036836Diabetes Research Center42025
P30CA016059Massey Cancer Center - Cancer Center Support Grant32025
P30CA033572Cancer Center Support Grant32025
P30DK045735Yale Diabetes Research Center32025

1 to 10 of 1,197Source NIH's project files

See all 1,197 nih grants

Papers1,685

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Epigenetic Insights in Pediatric Multiple Sclerosis: DNA Methylation Highlights an Involvement of Epstein-Barr Virus Infection and Host Immune Networks.Neurol Neuroimmunol Neuroinflamm202642789917PubTator, text miningPubMed
Changes in Muscle Mass and Quality Mediate the Effect of High-Calorie Intake on Clinical Outcomes.J Cachexia Sarcopenia Muscle202642590864PubTator, text miningPubMed
Loss of the cardiac-enriched mitochondrial transporter SLC25A34 promotes heart failure by attenuating fatty acid oxidation.J Mol Cell Biol202642573513PubTator, text miningPubMed
Aloe vera extract disrupts mitochondrial bioenergetics and suppresses HeLa cervical cancer cell proliferation: Transcriptomic and metabolic insights into cisplatin co-treatment.J Bioenerg Biomembr202642560575PubTator, text miningPubMed
Targeting USP8 with odoroside A regulates LXRβ-mediated fatty acid metabolic reprogramming against colorectal cancer.Acta Pharmacol Sin202642420594PubTator, text miningPubMed
EPAS1 is associated with human muscle fiber composition and endurance phenotypes.Physiol Rep202642157436PubTator, text miningPubMed
Transcriptome profile of keloid patients in Zunyi, China via multiple bioinformatic analyses.Burns202642127696PubTator, text miningPubMed
Disturbances in Central Sensitization Are Associated with Disease Severity and Alterations in Gene Expression Measured in the Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis.Int J Mol Sci202641898728PubTator, text miningPubMed
Transcriptome Analysis of miRNAs Involved in the Myogenic Differentiation of Goat Skeletal Muscle Satellite Cells.Cells202641892310PubTator, text miningPubMed
Unbiased Discovery of Genetic Determinants of Resilience to CAD: Insights From PROMISE and CATHGEN.JACC Adv202641855749PubTator, text miningPubMed

1 to 10 of 1,685

See all 1,685 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1375

GET https://conductscience.org/api/genes/v1/1375/patents?page=2