ConductScience.org, home

Gene · 1376

CPT2: carnitine palmitoyltransferase 2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. CPT2: carnitine palmitoyltransferase 2. Genes, record 1376. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1376

On this page

Gene

Symbol
CPT2
HGNC
Name
carnitine palmitoyltransferase 2
HGNC
NCBI Gene ID
1376
NCBI Gene
HGNC ID
HGNC:2330
HGNC
Ensembl
ENSG00000157184
NCBI Gene
Aliases
CPT1, CPTASE, IIAE4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P23786Carnitine O-palmitoyltransferase 2, mitochondrial6580Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21108P23786Espacenet
EP 4650780 A22025-11-198950P23786Espacenet
EP 4641201 A22025-10-299207P23786Espacenet
JP 2025517969 A2025-06-129207P23786Espacenet
JP 2025517970 A2025-06-128950P23786Espacenet
JP 2025062604 A2025-04-1412014P23786Espacenet
JP 2024123008 A2024-09-105290P23786Espacenet
JP 2023521663 A2023-05-25107P23786Espacenet
US 11446398 B22022-09-2012014P23786Espacenet
JP 2022524081 A2022-04-27114985P23786Espacenet

1 to 10 of 38

See all 38 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
PERHEXILINECHEMBL75880Carnitine palmitoyltransferase 2 inhibitorINHIBITORChEMBL
PERHEXILINE MALEATECHEMBL1334033Carnitine palmitoyltransferase 2 inhibitorINHIBITORChEMBL

Trials7

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04426578PERHEXILINEPHASE2ClinicalTrials.gov
NCT02862600PERHEXILINEPHASE22017-08-31ClinicalTrials.gov
NCT02431221PERHEXILINE MALEATEPHASE3ClinicalTrials.gov
NCT00989508PERHEXILINEPHASE2/PHASE3ClinicalTrials.gov
NCT00841139PERHEXILINEPHASE2ClinicalTrials.gov
NCT00628056PERHEXILINEPHASE1/PHASE2ClinicalTrials.gov
NCT00500552PERHEXILINEPHASE2ClinicalTrials.gov

NIH grants1,294

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCPT2 papersNewest fiscal year
P30DK056341Washington University Nutrition Obesity Research Center72025
P30CA021765Cancer Center Support Grant (CCSG)52025
ZIABC005562Xenobiotic receptors52025
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers52025
P30DK020579Diabetes Research Center42025
U01DK066174Chronic Kidney Disease in Children (CKiD)42025
P30CA008748Cancer Center Support Grant32025
P30CA043703Case Comprehensive Cancer Center Support Grant32025
P30DK020572Michigan Diabetes Research Center (MDRC)32025
P30DK072476Pennington/Louisiana NORC32025

1 to 10 of 1,294Source NIH's project files

See all 1,294 nih grants

Papers2,286

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular Weight-Dependent Functional and Antioxidant Properties of Glutamine-Rich Corn Protein Hydrolysate: Insights into the Predicted Structural Characteristics of Identified Peptides.Foods202642794068PubTator, text miningPubMed
Integrated Multi-Tissue Omics Identifies Acylcarnitine Accumulation as Shared Metabolic Marker of Diabetic Microangiopathy With Cross-Organ Validation.Invest Ophthalmol Vis Sci202642747258PubTator, text miningPubMed
Acute Kidney Injury and Extreme Rhabdomyolysis due to Carnitine Palmitoyltransferase II Deficiency: A Case Report.J Emerg Med202642721631PubTator, text miningPubMed
Novel environmental contaminant 6PPD-quinone promotes malignant phenotypes in colorectal cancer cells and identifies candidate response-associated genes.Chem Biol Interact202642624235PubTator, text miningPubMed
When to think of genetic causes for rhabdomyolysis? A Brazilian single-center exploratory study.Arq Neuropsiquiatr202642595308PubTator, text miningPubMed
The Role of Autophagy in the Pathogenesis of Mitochondrial Diseases.Cells202642587780PubTator, text miningPubMed
A covalent PFKL activator suppresses tumor growth.Nat Chem Biol202642557312PubTator, text miningPubMed
Toward standardized care: International expert survey on pregnancy management in long-chain fatty acid oxidation disorders and unmet needs.Mol Genet Metab202642424868PubTator, text miningPubMed
Long-Chain Fatty Acid Oxidation Disorder Genes: A Comprehensive Genetic Database of LC-FAOD Variants, Genotypes, and Phenotypes.Hum Mutat202642422157PubTator, text miningPubMed
Endothelial CPT2 loss impairs fatty acid oxidation and promotes renal fibrosis.Life Metab202642421976PubTator, text miningPubMed

1 to 10 of 2,286

See all 2,286 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1376

GET https://conductscience.org/api/genes/v1/1376/patents?page=2