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Gene · 1382

CRABP2: cellular retinoic acid binding protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CRABP2: cellular retinoic acid binding protein 2. Genes, record 1382. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1382

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Gene

Symbol
CRABP2
HGNC
Name
cellular retinoic acid binding protein 2
HGNC
NCBI Gene ID
1382
NCBI Gene
HGNC ID
HGNC:2339
HGNC
Ensembl
ENSG00000143320
NCBI Gene
Aliases
CRABP-II, RBP6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P29373Cellular retinoic acid-binding protein 213885Ensembl, GeneID, HGNC

Source UniProt

Patents67

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440812P29373Espacenet
JP 2026004568 A2026-01-1440813P29373Espacenet
EP 4650780 A22025-11-198413P29373Espacenet
JP 2025517970 A2025-06-128413P29373Espacenet
US 12024722 B22024-07-028P29373Espacenet
US 11446398 B22022-09-2013832P29373Espacenet
US 11446398 B22022-09-2013833P29373Espacenet
US 11446398 B22022-09-2013834P29373Espacenet
JP 2022524081 A2022-04-27116803P29373Espacenet
JP 2022524081 A2022-04-27116804P29373Espacenet

1 to 10 of 67

See all 67 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants871

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCRABP2 papersNewest fiscal year
P30CA068485Cancer Center Support Grant62025
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers62025
ZIABC005562Xenobiotic receptors52025
P30CA043703Case Comprehensive Cancer Center Support Grant42025
K12HD050121Research Career Development in Obstetrics and Gynecology32025
P30CA008748Cancer Center Support Grant32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025
R01DK046335Probing the biochemical mechanism of amyloid disease32025
R01DK122071RBP2 Biology and Pathobiology32025
R01NS098273Development and function of the meninges arachnoid barrier32025

1 to 10 of 871Source NIH's project files

See all 871 nih grants

Papers1,285

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Phase 1 study of KHK2455, a long-acting, potent and selective IDO1 inhibitor, in combination with avelumab in patients with locally advanced or metastatic urothelial carcinoma.J Immunother Cancer202642767768PubTator, text miningPubMed
Clinicopathologic features of spinal arachnoiditis in patients with surgically treated syringomyelia: A retrospective study of 60 cases.J Neuropathol Exp Neurol202642658566PubTator, text miningPubMed
Causal link between polymyositis and idiopathic pulmonary fibrosis in individuals of European ancestry: A Mendelian randomization and multi-omics study identifying mediators and drug targets.Medicine (Baltimore)202642629724PubTator, text miningPubMed
Cellular Retinoic Acid-Binding Protein 2 Promotes Ischemia-Induced Cardiac Fibroblast Activation and Fibrosis Through Suppression of MRE11-RAD50-NBS1-Mediated DNA Repair.J Am Heart Assoc202642535577PubTator, text miningPubMed
CRABP2 Promotes Lung Adenocarcinoma Through Retinoic Acid Pathway-Mediated NF-κB Activation.Front Biosci (Landmark Ed)202642530247PubTator, text miningPubMed
Oxymatrine Synergizes with 5-fluorouracil to Inhibit the Proliferation of A549 Cells by Targeting APE1.Curr Med Chem202642522309PubTator, text miningPubMed
The dual role of retinoic acid signaling in clear cell renal cell carcinoma and wilms tumor: A tale of two entities.Biochim Biophys Acta Rev Cancer202642492627PubTator, text miningPubMed
The CRABP2-MDK Signaling Axis Promotes Lung Adenocarcinoma (LUAD) Progression and Highlights Prognostic Biomarkers.Mol Carcinog202642472388PubTator, text miningPubMed
Single-cell and machine learning-based neural regulation signature for prognosis prediction and immunotherapy response in lung adenocarcinoma.Transl Oncol202642391672PubTator, text miningPubMed
Fatty acid-binding protein 5 (FABP5) modulates limbal epithelial cell homeostasis by regulating the expression of key genes under both normal and inflammatory conditions, in vitro.PLoS One202642048350PubTator, text miningPubMed

1 to 10 of 1,285

See all 1,285 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

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