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CREB1: cAMP responsive element binding protein 1

1 protein, 53 patents, 0 drugs, 0 trials, 14,204 NIH grants and 28,310 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCREB1HGNC
NamecAMP responsive element binding protein 1HGNC
NCBI Gene ID1385NCBI Gene
HGNC IDHGNC:2345HGNC
EnsemblENSG00000118260NCBI Gene
AliasesCREB, CREB-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P16220Cyclic AMP-responsive element-binding protein 13274Ensembl, GeneID, HGNCUniProt

Patents 53

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19930P16220Espacenet
JP 2025517970 A2025-06-12930P16220Espacenet
JP 2025062604 A2025-04-1411305P16220Espacenet
JP 2025062604 A2025-04-1411312P16220Espacenet
JP 2024123008 A2024-09-105273P16220Espacenet
JP 2024123008 A2024-09-105276P16220Espacenet
US 11884978 B22024-01-30473P16220Espacenet
US 11708396 B22023-07-252386P16220Espacenet
US 11708396 B22023-07-252389P16220Espacenet
US 11446398 B22022-09-2011305P16220Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 14204

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant802,025NIH's project files
P30CA008748Cancer Center Support Grant552,025NIH's project files
P01CA100730Retrovirus Models of Cancer262,025NIH's project files
P30AG017265USC/UCLA Center on Biodemography and Population Health242,025NIH's project files
P30CA086862Cancer Center Support Grant232,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award232,025NIH's project files
P30CA016058Cancer Center Support Grant202,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)202,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)192,025NIH's project files
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro182,025NIH's project files

Papers 28310

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824422PubTator, text miningPubMed
42809895PubTator, text miningPubMed
42805569PubTator, text miningPubMed
42805466PubTator, text miningPubMed
42802946PubTator, text miningPubMed
42801669PubTator, text miningPubMed
42801650PubTator, text miningPubMed
42794727PubTator, text miningPubMed
42793099PubTator, text miningPubMed
42792100PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license