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CREBBP: CREB binding lysine acetyltransferase

1 protein, 75 patents, 1 drug, 8 trials, 11,452 NIH grants and 20,658 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCREBBPHGNC
NameCREB binding lysine acetyltransferaseHGNC
NCBI Gene ID1387NCBI Gene
HGNC IDHGNC:2348HGNC
EnsemblENSG00000005339NCBI Gene
AliasesCBP, KAT3A, MKHK1, RSTS, RSTS1, RTSNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q92793Histone lysine acetyltransferase CREBBP2,442144Ensembl, GeneID, HGNCUniProt

Patents 75

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026135569 A2026-08-251Q92793Espacenet
WO 2026171694 A12026-08-201Q92793Espacenet
JP 2026004568 A2026-01-1442356Q92793Espacenet
EP 4650780 A22025-11-192057Q92793Espacenet
EP 4641201 A22025-10-291620Q92793Espacenet
JP 2025147176 A2025-10-0614847Q92793Espacenet
JP 2025137900 A2025-09-251Q92793Espacenet
WO 2025169375 A2025-08-141Q92793Espacenet
JP 2025517969 A2025-06-121620Q92793Espacenet
JP 2025517970 A2025-06-122057Q92793Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
PRI-724CHEMBL4297813CBP/beta catenin inhibitorINHIBITORChEMBL

Trials 8

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06144086PRI-724PHASE2ClinicalTrials.gov
NCT03620474PRI-724PHASE1/PHASE2ClinicalTrials.gov
NCT02828254PRI-724ClinicalTrials.gov
NCT02413853PRI-724PHASE2ClinicalTrials.gov
NCT02195440PRI-724PHASE1ClinicalTrials.gov
NCT01764477PRI-724PHASE1ClinicalTrials.gov
NCT01606579PRI-724PHASE1/PHASE2ClinicalTrials.gov
NCT01302405PRI-724PHASE1ClinicalTrials.gov

NIH grants 11452

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1622,025NIH's project files
P30CA016672Cancer Center Support Grant1182,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)792,025NIH's project files
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)382,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant272,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program262,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant262,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant252,025NIH's project files
P30CA016058Cancer Center Support Grant242,025NIH's project files
P30CA016086Cancer Center Support Grant222,025NIH's project files

Papers 20658

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826833PubTator, text miningPubMed
42817590PubTator, text miningPubMed
42809955PubTator, text miningPubMed
42801650PubTator, text miningPubMed
42793282PubTator, text miningPubMed
42771512PubTator, text miningPubMed
42762610PubTator, text miningPubMed
42753471PubTator, text miningPubMed
42750209PubTator, text miningPubMed
42745287PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license