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CRH: corticotropin releasing hormone

1 protein, 64 patents, 0 drugs, 0 trials, 8,198 NIH grants and 18,659 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCRHHGNC
Namecorticotropin releasing hormoneHGNC
NCBI Gene ID1392NCBI Gene
HGNC IDHGNC:2355HGNC
EnsemblENSG00000147571NCBI Gene
AliasesCRF, CRH1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06850Corticotropin-releasing hormone1965Ensembl, GeneID, HGNCUniProt

Patents 64

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192971P06850Espacenet
JP 2025169942 A2025-11-14932P06850Espacenet
JP 2025147176 A2025-10-063501P06850Espacenet
JP 2025529142 A2025-09-046007P06850Espacenet
US 12371689 B22025-07-296007P06850Espacenet
JP 2025517970 A2025-06-122971P06850Espacenet
JP 2025028160 A2025-02-283501P06850Espacenet
KR 1020250010750 A2025-01-213501P06850Espacenet
JP 2024112982 A2024-08-214597P06850Espacenet
JP 2024109657 A2024-08-143508P06850Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8198

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P60AA006420CNS Effects of Alcohol: Cellular Neurobiology762,025NIH's project files
P51OD011092Support for National Primate Research Center252,025NIH's project files
P51OD011132Emory National Primate Research Center252,025NIH's project files
P60AA010760Behavioral Genomics of Alcohol Neuroadaptation252,025NIH's project files
P60AA011605Molecular and Circuit Pathogenesis of Alcohol Use Disorders252,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award252,025NIH's project files
R01AA013892Chronic Alcohol and Brain Stress Circuit Response242,025NIH's project files
ZIAAA000301Integrative genetics of behavior with high throughput technologies232,025NIH's project files
T32AA007456NEUROPSYCHOPHARMACOLOGY: MULTIDISCIPLINARY TRAINING212,025NIH's project files
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)192,025NIH's project files

Papers 18659

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42819002PubTator, text miningPubMed
42808100PubTator, text miningPubMed
42794859PubTator, text miningPubMed
42762694PubTator, text miningPubMed
42740624PubTator, text miningPubMed
42732957PubTator, text miningPubMed
42720068PubTator, text miningPubMed
42716024PubTator, text miningPubMed
42688078PubTator, text miningPubMed
42687004PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license