Gene · 139341
FUNDC1: FUN14 domain containing 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FUNDC1: FUN14 domain containing 1. Genes, record 139341. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/139341
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8IVP5 | FUN14 domain-containing protein 1 | 155 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents14
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025024198 A | 2025-02-19 | 12691 | Q8IVP5 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 33075 | Q8IVP5 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 136046 | Q8IVP5 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 4223 | Q8IVP5 | Espacenet |
| JP 2021018154 A | 2021-02-15 | 652 | Q8IVP5 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 937 | Q8IVP5 | Espacenet |
| US 9827332 B2 | 2017-11-28 | 12691 | Q8IVP5 | Espacenet |
| JP 2017121243 A | 2017-07-13 | 56659 | Q8IVP5 | Espacenet |
| US 9254311 B2 | 2016-02-09 | 12691 | Q8IVP5 | Espacenet |
| JP 2015513912 A | 2015-05-18 | 56659 | Q8IVP5 | Espacenet |
1 to 10 of 14
See all 14 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants580
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FUNDC1 papers | Newest fiscal year |
|---|---|---|---|
| P30AG028740 | University of Florida Older Americans Independence Center (OAIC) | 3 | 2025 |
| P30DK020579 | Diabetes Research Center | 3 | 2025 |
| R01CA142746 | Subcellular enzyme-instructed self-assembly for molecular anticancer nanomedicines | 3 | 2025 |
| R01CA200310 | BNIP3 and BNIP3L (NIX) in lipid homeostasis and growth control in the liver | 3 | 2025 |
| R01DE016572 | Ceramide Signaling in the Regulation of Head & Neck Cancer Cell Death and Therapy | 3 | 2025 |
| R01DK079879 | Autophagy in liver injury | 3 | 2025 |
| R01HL091469 | Cysteine oxidation in the heart | 3 | 2025 |
| R01NS101628 | Dendrite regulation by the mitochondrial kinase PINK1: Implications for PD/LBD | 3 | 2025 |
| R35GM131919 | The mechanism and regulation of autophagy | 3 | 2025 |
| T32CA009594 | Multi-Disciplinary Training Grant in Cancer Research | 3 | 2025 |
1 to 10 of 580Source NIH's project files
See all 580 nih grantsPapers1,296
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Bibliometric Review of Research Trends and Therapeutic Potential Reveals Natural Products as Major Regulators of Mitophagy in Kidney Disease. | Mini Rev Med Chem | 2026 | 42817106 | PubTator, text mining | PubMed |
| SRC Promotes High Glucose-Induced Retinal Endothelial Dysfunction by Suppressing FUNDC1-Mediated Mitophagy in Diabetic Retinopathy. | Curr Eye Res | 2026 | 42806608 | PubTator, text mining | PubMed |
| Transcriptional Regulation of Receptor-Mediated Mitophagy in Sunitinib-Resistant Renal Cancer Cells: Response to Succinic Acid. | Pharmaceuticals (Basel) | 2026 | 42797377 | PubTator, text mining | PubMed |
| FUNDC1 Attenuates UVA-Induced Skin Photoaging by Regulating Mitophagy and P53 Stability. | Antioxidants (Basel) | 2026 | 42792104 | PubTator, text mining | PubMed |
| Mitophagy in idiopathic pulmonary fibrosis: from molecular mechanisms to therapeutic opportunities. | Front Cell Dev Biol | 2026 | 42769024 | PubTator, text mining | PubMed |
| Mitophagy as an active regulator of cardiac metabolic reprogramming. | Front Cardiovasc Med | 2026 | 42746169 | PubTator, text mining | PubMed |
| Piezo1 as a Key Mechanosensitive Ion Channel Linking Mechanical Overload to Mitochondrial Dysfunction, Mitophagy, and Immunometabolic Dysregulation in Osteoarthritis. | Cells | 2026 | 42738805 | PubTator, text mining | PubMed |
| Targeting FUNDC1 Enhances Radiosensitivity of Esophageal Squamous Cell Carcinoma by Suppressing Mitochondrial Function. | Curr Gene Ther | 2026 | 42634168 | PubTator, text mining | PubMed |
| Transcriptomic and genetic evidence highlights EHHADH in a FUNDC1-associated mitochondrial network in diabetic nephropathy. | Metabol Open | 2026 | 42633340 | PubTator, text mining | PubMed |
| Upregulation of serum circular RNA FUNDC1 and TNF-α in Behçet's disease: potential diagnostic biomarkers. | Sci Rep | 2026 | 42632834 | PubTator, text mining | PubMed |
1 to 10 of 1,296
See all 1,296 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/139341
GET https://conductscience.org/api/genes/v1/139341/patents