Gene · 1395
CRHR2: corticotropin releasing hormone receptor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CRHR2: corticotropin releasing hormone receptor 2. Genes, record 1395. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1395
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13324 | Corticotropin-releasing hormone receptor 2 | 411 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 42306 | Q13324 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3516 | Q13324 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1121 | Q13324 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6010 | Q13324 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1121 | Q13324 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6010 | Q13324 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 3516 | Q13324 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 3516 | Q13324 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 3523 | Q13324 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 20080 | Q13324 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,380
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CRHR2 papers | Newest fiscal year |
|---|---|---|---|
| P60AA010760 | Behavioral Genomics of Alcohol Neuroadaptation | 15 | 2025 |
| P60AA006420 | CNS Effects of Alcohol: Cellular Neurobiology | 13 | 2025 |
| P51OD011092 | Support for National Primate Research Center | 8 | 2025 |
| R01AR073004 | Mechanism of action and function of novel secosteroid 20(OH)D3 in the skin | 5 | 2025 |
| U01AA013498 | 9/10 Electrophysiology of Alcohol in Extended Amygdala | 5 | 2025 |
| P51OD011106 | Wisconsin National Primate Research Center Support | 4 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 4 | 2025 |
| P60AA007611 | Center on Genetic Determinants of Alcohol Ingestion and Responses to Alcohol | 4 | 2025 |
| P60AA011605 | Molecular and Circuit Pathogenesis of Alcohol Use Disorders | 4 | 2025 |
| R37AA017447 | Gene-environment interaction: the brain CRF system in alcohol preferring msP rats | 4 | 2025 |
1 to 10 of 1,380Source NIH's project files
See all 1,380 nih grantsPapers1,856
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Corticotropin-releasing factor (CRF) in brain aging: from mitochondrial dysfunction to inflammaging. | Front Aging Neurosci | 2026 | 42602249 | PubTator, text mining | PubMed |
| GH responsiveness to corticotropin-releasing hormone identifies corticotroph-like somatotroph adenomas in acromegaly. | Pituitary | 2026 | 42384227 | PubTator, text mining | PubMed |
| Association of Stress-Related Genetic Polymorphisms and Stressful Life Events With Alcohol Use Disorder in a Brazilian Population. | Stress Health | 2026 | 42375127 | PubTator, text mining | PubMed |
| Single-cell Dissection of Microglial Heterogeneity Reveals Subtype-driven Immune-metabolic Crosstalk in Major Depressive Disorder. | Curr Neuropharmacol | 2026 | 42163665 | PubTator, text mining | PubMed |
| A unifying theory of brain signaling and its possible role in acquired chronic disease. | Front Neurosci | 2026 | 42063971 | PubTator, text mining | PubMed |
| Cr-LiF as a high energy density conversion-type cathode for Li-ion solid-state batteries. | Commun Mater | 2026 | 42040974 | PubTator, text mining | PubMed |
| Correction: Nazarloo et al. Oxytocin, Vasopressin and Stress: A Hormetic Perspective. Curr. Issues Mol. Biol. 2025, 47, 632. | Curr Issues Mol Biol | 2026 | 41899490 | PubTator, text mining | PubMed |
| Interim analysis of all-case post-marketing surveillance study in Japan: lecanemab in patients with early Alzheimer's disease. | J Prev Alzheimers Dis | 2026 | 41849958 | PubTator, text mining | PubMed |
| Emerging roles of spexin in cardiovascular homeostasis. | Front Cardiovasc Med | 2026 | 41788558 | PubTator, text mining | PubMed |
| PVNCRF Neurons Regulate Migraine-Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons. | Adv Sci (Weinh) | 2026 | 41762709 | PubTator, text mining | PubMed |
1 to 10 of 1,856
See all 1,856 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1395
GET https://conductscience.org/api/genes/v1/1395/patents?page=2