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SIRPA: signal regulatory protein alpha

1 protein, 231 patents, 0 drugs, 0 trials, 2,975 NIH grants and 5,532 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSIRPAHGNC
Namesignal regulatory protein alphaHGNC
NCBI Gene ID140885NCBI Gene
HGNC IDHGNC:9662HGNC
EnsemblENSG00000198053NCBI Gene
AliasesBIT, CD172A, CD172a, MFR, MYD-1, MYD1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P78324Tyrosine-protein phosphatase non-receptor type substrate 150415Ensembl, GeneID, HGNCUniProt

Patents 231

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4810510 A22026-09-2312P78324Espacenet
JP 2026074385 A2026-05-0156P78324Espacenet
WO 2026027944 A12026-02-0534P78324Espacenet
JP 2026016481 A2026-02-0331P78324Espacenet
WO 2025262304 A12025-12-2639P78324Espacenet
JP 2025541309 A2025-12-1814P78324Espacenet
EP 4662236 A22025-12-1777P78324Espacenet
JP 2025181864 A2025-12-111006P78324Espacenet
KR 1020250172692 A2025-12-0931P78324Espacenet
US 12486329 B22025-12-0256P78324Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2975

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant372,025NIH's project files
P01AI045897A Tolerance Approach to Xenotransplantation262,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award172,025NIH's project files
P30CA016672Cancer Center Support Grant152,025NIH's project files
P30CA034196Cancer Center Support (CORE) Grant152,025NIH's project files
T32CA009302Leveraging innovative technologies in basic and clinical cancer research152,025NIH's project files
T32AI007290Molecular and Cellular Immunobiology132,025NIH's project files
P30CA091842Cancer Center Support Grant122,025NIH's project files
P30CA124435Stanford Cancer Institute122,025NIH's project files
R01DK079392Intestinal Inflammation: Signaling proteins and the rate of PMN transmigration122,025NIH's project files

Papers 5532

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42816832PubTator, text miningPubMed
42804006PubTator, text miningPubMed
42798844PubTator, text miningPubMed
42790655PubTator, text miningPubMed
42786305PubTator, text miningPubMed
42773727PubTator, text miningPubMed
42761652PubTator, text miningPubMed
42761049PubTator, text miningPubMed
42742063PubTator, text miningPubMed
42725506PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license