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Gene · 1421

CRYGD: crystallin gamma D

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CRYGD: crystallin gamma D. Genes, record 1421. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1421

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Gene

Symbol
CRYGD
HGNC
Name
crystallin gamma D
HGNC
NCBI Gene ID
1421
NCBI Gene
HGNC ID
HGNC:2411
HGNC
Ensembl
ENSG00000118231
NCBI Gene
Aliases
CACA, CCA3, CCP, CRYG4, CTRCT4, PCC, cry-g-D
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P07320Gamma-crystallin D17416Ensembl, GeneID, HGNC

Source UniProt

Patents12

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442411P07320Espacenet
EP 4484957 A12025-01-0179P07320Espacenet
WO 2023162878 A2023-08-3179P07320Espacenet
US 11446398 B22022-09-2020267P07320Espacenet
JP 2022092366 A2022-06-22806P07320Espacenet
JP 2022524081 A2022-04-27123238P07320Espacenet
US 11078247 B22021-08-032622P07320Espacenet
JP 2019054813 A2019-04-11222846P07320Espacenet
JP 2017121241 A2017-07-13222846P07320Espacenet
JP 2015516143 A2015-06-08222846P07320Espacenet

1 to 10 of 12

See all 12 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants680

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCRYGD papersNewest fiscal year
ZIAEY000255Molecular Structure and Function of Crystallins122025
ZIAEY000281Clinical/molecular Studies In Families With Congenital Or Hereditary Cataracts102025
P30EY008126Core Grant in Vision Research62025
P30EY010572Ophthalmology Core Facility42025
R01DK079895Structural mechanism of diabetic amyloid formation42025
P30EY003039UAB Core Grant for Vision Research32025
R01EY013462The Role of Aquaporins in Lens Structure and Function32025
R35GM118091Quantitative, Mechanistic Studies of Biomolecular Recognition32025
ZIAAA000550Neurobiology of Drug Reward and Addiction32025
ZIAHL001452Time Resolved Fluorescence Spectroscopy32025

1 to 10 of 680Source NIH's project files

See all 680 nih grants

Papers1,389

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The Application of Nurse-Led Bedside Critical Care Ultrasound in Paediatric and Neonatal Nursing Practice: A Scoping Review.Nurs Crit Care202642806280PubTator, text miningPubMed
Quality aspects of dementia care counselling from the perspective of people living with dementia, their care partners and healthcare professionals: protocol for a participatory scoping review.BMJ Open202642772872PubTator, text miningPubMed
Public health policies for children and youth with special health care needs in OECD member countries and Brazil: A scoping review.PLoS One202642758769PubTator, text miningPubMed
Wearable, cuffless, and portable devices for blood pressure monitoring (2015-2025): a scoping review of technologies, calibration, clinical validation, and regulatory frameworks.Front Digit Health202642656502PubTator, text miningPubMed
Validation of an Arabic Instrument for the Assessment of Patient-Centered Care Among Patients with Diabetes in the Primary Healthcare Setting in the Kingdom of Saudi Arabia.Healthcare (Basel)202642651279PubTator, text miningPubMed
Case Report: Identification of a CRYGD variant in a family with congenital cataract.Front Med (Lausanne)202642359092PubTator, text miningPubMed
Dimerization of natively folded molecules drives misfolding and aggregation in Cys-depleted variants of cataract-associated human lens γD-crystallin.J Biol Chem202642264090PubTator, text miningPubMed
eHealth literacy in emergency care: a scoping review.BMC Health Serv Res202642121136PubTator, text miningPubMed
Identification of Two Novel Variants in CRYGD and OCRL Genes in the Chinese Population With Hereditary Congenital Cataracts Using Whole Exome Sequencing.Hum Mutat202642111499PubTator, text miningPubMed
Evaluating gene-disease relationship strength in crystallin genes in association with pediatric cataracts.Ophthalmic Genet202642091610PubTator, text miningPubMed

1 to 10 of 1,389

See all 1,389 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1421

GET https://conductscience.org/api/genes/v1/1421/patents