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CSF1: colony stimulating factor 1

1 protein, 169 patents, 2 drugs, 11 trials, 11,152 NIH grants and 23,393 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCSF1HGNC
Namecolony stimulating factor 1HGNC
NCBI Gene ID1435NCBI Gene
HGNC IDHGNC:2432HGNC
EnsemblENSG00000184371NCBI Gene
AliasesCSF-1, M-CSF, MCSF, MGC31930, PG-M-CSFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P09603Macrophage colony-stimulating factor 15548Ensembl, GeneID, HGNCUniProt

Patents 169

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026086743 A2026-05-26206P09603Espacenet
JP 2025172069 A2025-11-20585P09603Espacenet
JP 2025172069 A2025-11-20588P09603Espacenet
EP 4650780 A22025-11-195723P09603Espacenet
EP 4641202 A22025-10-29308P09603Espacenet
EP 4641203 A22025-10-29174P09603Espacenet
JP 2025147176 A2025-10-063577P09603Espacenet
JP 2025147176 A2025-10-063578P09603Espacenet
JP 2025147176 A2025-10-0616769P09603Espacenet
WO 2025186446 A12025-09-1239P09603Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
MCS-110CHEMBL2109512Macrophage colony-stimulating factor 1 inhibitorINHIBITORChEMBL
PD-360324CHEMBL2109513Macrophage colony-stimulating factor 1 inhibitorINHIBITORChEMBL

Trials 11

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT03742349MCS-110PHASE1ClinicalTrials.gov
NCT03694977MCS-110PHASE2ClinicalTrials.gov
NCT03455764MCS-110PHASE1/PHASE22024-07-31ClinicalTrials.gov
NCT03285607MCS-110PHASE1ClinicalTrials.gov
NCT02554812PD-360324PHASE1/PHASE22024-07-30ClinicalTrials.gov
NCT02435680MCS-110PHASE22021-06-21ClinicalTrials.gov
NCT01732211PD-360324PHASE22020-01-06ClinicalTrials.gov
NCT01643850MCS-110PHASE22020-02-27ClinicalTrials.gov
NCT01470313PD-360324PHASE1ClinicalTrials.gov
NCT00757757MCS-110PHASE1/PHASE2ClinicalTrials.gov

NIH grants 11152

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant932,025NIH's project files
P30CA016672Cancer Center Support Grant712,025NIH's project files
P30CA013330Cancer Center Support Grant672,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)452,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award362,025NIH's project files
R01AR046713Cytokine regulation of RA synoviocyte phenotype312,025NIH's project files
R01AI044938Inhibition of STAT3 and inflammatory cytokine production292,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program282,025NIH's project files
R01AI046712Activation of Macrophages in Human Autoimmune Diseases282,025NIH's project files
P30CA016058Cancer Center Support Grant262,025NIH's project files

Papers 23393

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821460PubTator, text miningPubMed
42819224PubTator, text miningPubMed
42810676PubTator, text miningPubMed
42806659PubTator, text miningPubMed
42803886PubTator, text miningPubMed
42785104PubTator, text miningPubMed
42780184PubTator, text miningPubMed
42763286PubTator, text miningPubMed
42762141PubTator, text miningPubMed
42754413PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license