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CSF1R: colony stimulating factor 1 receptor

1 protein, 325 patents, 21 drugs, 774 trials, 6,769 NIH grants and 12,352 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCSF1RHGNC
Namecolony stimulating factor 1 receptorHGNC
NCBI Gene ID1436NCBI Gene
HGNC IDHGNC:2433HGNC
EnsemblENSG00000182578NCBI Gene
AliasesBANDDOS, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, GPSC, HDLS, HDLS1, M-CSF-RNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P07333Macrophage colony-stimulating factor 1 receptor97226Ensembl, GeneID, HGNCUniProt

Patents 325

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026174322 A12026-08-203P07333Espacenet
JP 2026004568 A2026-01-1441911P07333Espacenet
JP 2025186316 A2025-12-2385P07333Espacenet
EP 4650780 A22025-11-193283P07333Espacenet
WO 2025228986 A12025-11-0652P07333Espacenet
EP 4644537 A12025-11-0552P07333Espacenet
WO 2025226637 A12025-10-301P07333Espacenet
EP 4641201 A22025-10-292857P07333Espacenet
US 12454573 B22025-10-281P07333Espacenet
WO 2025210175 A12025-10-091P07333Espacenet

Drugs 21

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AMG-820CHEMBL2109322Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL
ARRY-382CHEMBL3644252Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL
AXATILIMABCHEMBL4594608Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL
CABIRALIZUMABCHEMBL4297713Macrophage colony stimulating factor receptor antagonistANTAGONISTChEMBL
CT-1578CHEMBL2035185Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL
EDICOTINIBCHEMBL3674570Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL
EMACTUZUMABCHEMBL3545370Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL
ENMD-2076CHEMBL482968Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL
IMC-CS4CHEMBL2109323Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL
LINIFANIBCHEMBL223360Macrophage colony stimulating factor receptor inhibitorINHIBITORChEMBL

Trials 774

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07511062AXATILIMABPHASE1ClinicalTrials.gov
NCT07478991QUIZARTINIBPHASE3ClinicalTrials.gov
NCT07477457SUNITINIBPHASE2ClinicalTrials.gov
NCT07444619PAZOPANIBPHASE1ClinicalTrials.gov
NCT07218926SUNITINIBPHASE3ClinicalTrials.gov
NCT07181382SERALUTINIBPHASE3ClinicalTrials.gov
NCT07128381AXATILIMABPHASE1/PHASE2ClinicalTrials.gov
NCT07124078AXATILIMABPHASE2ClinicalTrials.gov
NCT07087158PAZOPANIBPHASE2ClinicalTrials.gov
NCT07015853AXATILIMABPHASE2ClinicalTrials.gov

NIH grants 6769

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1162,025NIH's project files
P30CA016672Cancer Center Support Grant742,025NIH's project files
P30CA013330Cancer Center Support Grant542,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)512,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program252,025NIH's project files
P30CA091842Cancer Center Support Grant242,025NIH's project files
P30CA016058Cancer Center Support Grant192,025NIH's project files
R01NS083801Origins, properties, and therapeutic potential of cells that repopulate the microglia-depleted adult brain192,025NIH's project files
P30CA006973Regional Oncology Research Center172,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award172,025NIH's project files

Papers 12352

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827143PubTator, text miningPubMed
42822756PubTator, text miningPubMed
42813062PubTator, text miningPubMed
42806659PubTator, text miningPubMed
42763389PubTator, text miningPubMed
42761463PubTator, text miningPubMed
42761428PubTator, text miningPubMed
42758973PubTator, text miningPubMed
42754413PubTator, text miningPubMed
42751261PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license