ConductScience.org, home

Library / Genes

CSF2: colony stimulating factor 2

1 protein, 718 patents, 6 drugs, 42 trials, 22,649 NIH grants and 65,745 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCSF2HGNC
Namecolony stimulating factor 2HGNC
NCBI Gene ID1437NCBI Gene
HGNC IDHGNC:2434HGNC
EnsemblENSG00000164400NCBI Gene
AliasesCSF, GM-CSF, GMCSFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P04141Granulocyte-macrophage colony-stimulating factor14411Ensembl, GeneID, HGNCUniProt

Patents 718

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026177163 A2026-08-278P04141Espacenet
EP 4774003 A12026-07-155P04141Espacenet
EP 4750905 A22026-06-033P04141Espacenet
JP 2026086743 A2026-05-26135P04141Espacenet
JP 2026062601 A52026-04-2413P04141Espacenet
JP 2026509256 A2026-03-1765P04141Espacenet
JP 2026508054 A2026-03-1033P04141Espacenet
US 12564633 B22026-03-036P04141Espacenet
EP 4698223 A22026-02-2521P04141Espacenet
WO 2025259466 A12025-12-181P04141Espacenet

Drugs 6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
GIMSILUMABCHEMBL2109430Granulocyte-macrophage colony-stimulating factor inhibitorINHIBITORChEMBL
LENZILUMABCHEMBL3707325Granulocyte-macrophage colony-stimulating factor inhibitorINHIBITORChEMBL
NAMILUMABCHEMBL1743044Granulocyte-macrophage colony-stimulating factor inhibitorINHIBITORChEMBL
OTILIMABCHEMBL2109433Granulocyte-macrophage colony-stimulating factor inhibitorINHIBITORChEMBL
PEXASTIMOGENE DEVACIREPVECCHEMBL3039547Granulocyte-macrophage colony-stimulating factor vaccine antigenVACCINE ANTIGENChEMBL
PLONMARLIMABCHEMBL4650518Granulocyte-macrophage colony-stimulating factor antagonistANTAGONISTChEMBL

Trials 42

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05351554NAMILUMABPHASE22025-04-17ClinicalTrials.gov
NCT05314517NAMILUMABPHASE22025-09-12ClinicalTrials.gov
NCT04849260PEXASTIMOGENE DEVACIREPVECPHASE1/PHASE2ClinicalTrials.gov
NCT04583969LENZILUMABPHASE22023-06-05ClinicalTrials.gov
NCT04457856PLONMARLIMABPHASE1ClinicalTrials.gov
NCT04351243GIMSILUMABPHASE22021-12-10ClinicalTrials.gov
NCT04351152LENZILUMABPHASE3ClinicalTrials.gov
NCT04341116PLONMARLIMABPHASE2/PHASE32023-05-06ClinicalTrials.gov
NCT04333147OTILIMABPHASE32024-02-07ClinicalTrials.gov
NCT04205851GIMSILUMABPHASE1ClinicalTrials.gov

NIH grants 22649

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2962,025NIH's project files
P30CA016672Cancer Center Support Grant2372,025NIH's project files
P30CA006973Regional Oncology Research Center1192,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award882,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)842,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program802,025NIH's project files
P30CA016058Cancer Center Support Grant792,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support732,025NIH's project files
P30CA047904Cancer Center Support Grant722,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant702,025NIH's project files

Papers 65745

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827143PubTator, text miningPubMed
42825912PubTator, text miningPubMed
42824810PubTator, text miningPubMed
42819108PubTator, text miningPubMed
42807340PubTator, text miningPubMed
42806494PubTator, text miningPubMed
42796630PubTator, text miningPubMed
42794533PubTator, text miningPubMed
42789389PubTator, text miningPubMed
42786914PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license