Gene · 1438
CSF2RA: colony stimulating factor 2 receptor subunit alpha
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CSF2RA: colony stimulating factor 2 receptor subunit alpha. Genes, record 1438. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1438
On this page
Gene
- Aliases
- CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMCSFR-alpha, GMR, GMR-alpha, SMDP4, alphaGMR
- NCBI Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P15509 | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha | 400 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents117
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026510989 A | 2026-04-10 | 69 | P15509 | Espacenet |
| EP 4705273 A2 | 2026-03-11 | 308 | P15509 | Espacenet |
| JP 2026027383 A | 2026-02-18 | 27 | P15509 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41921 | P15509 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41922 | P15509 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41926 | P15509 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10467 | P15509 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10796 | P15509 | Espacenet |
| EP 4633648 A1 | 2025-10-22 | 39 | P15509 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3591 | P15509 | Espacenet |
1 to 10 of 117
See all 117 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials449
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07537400 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT07437963 | SARGRAMOSTIM | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT07342322 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT07090538 | SARGRAMOSTIM | EARLY_PHASE1 | ClinicalTrials.gov | |
| NCT07085338 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT07078604 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT06989333 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT06799026 | SARGRAMOSTIM | PHASE1 | ClinicalTrials.gov | |
| NCT06608303 | SARGRAMOSTIM | ClinicalTrials.gov | ||
| NCT06528496 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov |
1 to 10 of 449
See all 449 trialsNIH grants1,522
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CSF2RA papers | Newest fiscal year |
|---|---|---|---|
| P40OD018537 | Bloomington Drosophila Stock Center at Indiana University | 17 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| R01CA154947 | Defining Pathogenic Mechanisms and Therapeutic Opportunities for Langerhans Cell Histiocytosis | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 4 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 4 | 2025 |
| R01EY020866 | Unfolded Protein Response in Drosophila models of Retinitis Pigmentosa | 4 | 2025 |
| R01NS099280 | Hexanucleotide repeat translation in ALS and Frontotemporal Dementia | 4 | 2025 |
| ZIAAI001130 | Eosinophils and Eosinophil Activation in the Pathogenesis of Human Disease | 4 | 2025 |
| P30AG072931 | Michigan Alzheimer's Disease Research Center | 3 | 2025 |
1 to 10 of 1,522Source NIH's project files
See all 1,522 nih grantsPapers2,071
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Microbial ammonia oxidation-driven hydroxyl radical generation enables efficient degradation of antibiotic resistance genes. | Environ Res | 2026 | 42498107 | PubTator, text mining | PubMed |
| CRISPR screening identifies DTX4 governing alveolar macrophage cholesterol efflux in pulmonary alveolar proteinosis. | JCI Insight | 2026 | 42484372 | PubTator, text mining | PubMed |
| Single nuclear RNA sequencing shows altered microglial and astrocytic functions in post-mortem Parkinson's disease tissue. | BMC Genom Data | 2026 | 42401827 | PubTator, text mining | PubMed |
| Unraveling giant cell arteritis: From immunopathology to emerging targeted therapies (2026 update). | Autoimmun Rev | 2026 | 42288301 | PubTator, text mining | PubMed |
| Integrated bioinformatics analysis reveals cytokine dysregulation, pathway alterations, and machine learning identification of diagnostic biomarkers in sepsis. | Integr Biol (Camb) | 2026 | 42247642 | PubTator, text mining | PubMed |
| Endothelial progenitor cell numbers vary in newborns and adults; anti-gm-CSFα (CD116) antibody as a novel marker for EPC enumeration. | Innate Immun | 2026 | 41960927 | PubTator, text mining | PubMed |
| Serum neurofilament light chain in hydrocephalus and surgical controls: baseline comparison and 24-hour perioperative dynamics under general anesthesia. | Neurosurg Rev | 2026 | 41915252 | PubTator, text mining | PubMed |
| Discriminating nodular pulmonary alveolar proteinosis from lung adenocarcinoma with radiomic model and multimodal model. | Ther Adv Respir Dis | 2026 | 41905780 | PubTator, text mining | PubMed |
| Colony-stimulating factor-2 triggers NNMT-dependent myofibroblast activation in head and neck cancer. | Oncogene | 2026 | 41896590 | PubTator, text mining | PubMed |
| Modeling Chronic BaP Exposure in Bronchial Epithelial Cells Reveals Multi-Scale Drivers of Early Preneoplastic Reprogramming. | Cells | 2026 | 41892355 | PubTator, text mining | PubMed |
1 to 10 of 2,071
See all 2,071 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1438
GET https://conductscience.org/api/genes/v1/1438/patents?page=2