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Gene · 1438

CSF2RA: colony stimulating factor 2 receptor subunit alpha

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CSF2RA: colony stimulating factor 2 receptor subunit alpha. Genes, record 1438. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1438

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Gene

Symbol
CSF2RA
HGNC
Name
colony stimulating factor 2 receptor subunit alpha
HGNC
NCBI Gene ID
1438
NCBI Gene
HGNC ID
HGNC:2435
HGNC
Ensembl
ENSG00000198223, ENSG00000292357
NCBI Gene
Aliases
CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMCSFR-alpha, GMR, GMR-alpha, SMDP4, alphaGMR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P15509Granulocyte-macrophage colony-stimulating factor receptor subunit alpha4002Ensembl, GeneID, HGNC

Source UniProt

Patents117

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026510989 A2026-04-1069P15509Espacenet
EP 4705273 A22026-03-11308P15509Espacenet
JP 2026027383 A2026-02-1827P15509Espacenet
JP 2026004568 A2026-01-1441921P15509Espacenet
JP 2026004568 A2026-01-1441922P15509Espacenet
JP 2026004568 A2026-01-1441926P15509Espacenet
EP 4650780 A22025-11-1910467P15509Espacenet
EP 4641201 A22025-10-2910796P15509Espacenet
EP 4633648 A12025-10-2239P15509Espacenet
JP 2025147176 A2025-10-063591P15509Espacenet

1 to 10 of 117

See all 117 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
MAVRILIMUMABCHEMBL1743039Granulocyte-macrophage colony-stimulating factor receptor antagonistANTAGONISTChEMBL
SARGRAMOSTIMCHEMBL1201670Granulocyte-macrophage colony-stimulating factor receptor agonistAGONISTChEMBL

Trials449

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07537400SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT07437963SARGRAMOSTIMPHASE1/PHASE2ClinicalTrials.gov
NCT07342322SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT07090538SARGRAMOSTIMEARLY_PHASE1ClinicalTrials.gov
NCT07085338SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT07078604SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT06989333SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT06799026SARGRAMOSTIMPHASE1ClinicalTrials.gov
NCT06608303SARGRAMOSTIMClinicalTrials.gov
NCT06528496SARGRAMOSTIMPHASE2ClinicalTrials.gov

1 to 10 of 449

See all 449 trials

NIH grants1,522

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCSF2RA papersNewest fiscal year
P40OD018537Bloomington Drosophila Stock Center at Indiana University172025
P30CA008748Cancer Center Support Grant122025
R01CA154947Defining Pathogenic Mechanisms and Therapeutic Opportunities for Langerhans Cell Histiocytosis62025
P30CA016672Cancer Center Support Grant52025
P30CA033572Cancer Center Support Grant42025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease42025
R01EY020866Unfolded Protein Response in Drosophila models of Retinitis Pigmentosa42025
R01NS099280Hexanucleotide repeat translation in ALS and Frontotemporal Dementia42025
ZIAAI001130Eosinophils and Eosinophil Activation in the Pathogenesis of Human Disease42025
P30AG072931Michigan Alzheimer's Disease Research Center32025

1 to 10 of 1,522Source NIH's project files

See all 1,522 nih grants

Papers2,071

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Microbial ammonia oxidation-driven hydroxyl radical generation enables efficient degradation of antibiotic resistance genes.Environ Res202642498107PubTator, text miningPubMed
CRISPR screening identifies DTX4 governing alveolar macrophage cholesterol efflux in pulmonary alveolar proteinosis.JCI Insight202642484372PubTator, text miningPubMed
Single nuclear RNA sequencing shows altered microglial and astrocytic functions in post-mortem Parkinson's disease tissue.BMC Genom Data202642401827PubTator, text miningPubMed
Unraveling giant cell arteritis: From immunopathology to emerging targeted therapies (2026 update).Autoimmun Rev202642288301PubTator, text miningPubMed
Integrated bioinformatics analysis reveals cytokine dysregulation, pathway alterations, and machine learning identification of diagnostic biomarkers in sepsis.Integr Biol (Camb)202642247642PubTator, text miningPubMed
Endothelial progenitor cell numbers vary in newborns and adults; anti-gm-CSFα (CD116) antibody as a novel marker for EPC enumeration.Innate Immun202641960927PubTator, text miningPubMed
Serum neurofilament light chain in hydrocephalus and surgical controls: baseline comparison and 24-hour perioperative dynamics under general anesthesia.Neurosurg Rev202641915252PubTator, text miningPubMed
Discriminating nodular pulmonary alveolar proteinosis from lung adenocarcinoma with radiomic model and multimodal model.Ther Adv Respir Dis202641905780PubTator, text miningPubMed
Colony-stimulating factor-2 triggers NNMT-dependent myofibroblast activation in head and neck cancer.Oncogene202641896590PubTator, text miningPubMed
Modeling Chronic BaP Exposure in Bronchial Epithelial Cells Reveals Multi-Scale Drivers of Early Preneoplastic Reprogramming.Cells202641892355PubTator, text miningPubMed

1 to 10 of 2,071

See all 2,071 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1438

GET https://conductscience.org/api/genes/v1/1438/patents?page=2