Gene · 1439
CSF2RB: colony stimulating factor 2 receptor subunit beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CSF2RB: colony stimulating factor 2 receptor subunit beta. Genes, record 1439. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1439
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P32927 | Cytokine receptor common subunit beta | 897 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents146
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4795064 A1 | 2026-08-26 | 7 | P32927 | Espacenet |
| JP 2026510989 A | 2026-04-10 | 70 | P32927 | Espacenet |
| EP 4705273 A2 | 2026-03-11 | 309 | P32927 | Espacenet |
| JP 2026027383 A | 2026-02-18 | 26 | P32927 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41929 | P32927 | Espacenet |
| JP 2026000906 A | 2026-01-06 | 100 | P32927 | Espacenet |
| JP 2025172069 A | 2025-11-20 | 135 | P32927 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11764 | P32927 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 12495 | P32927 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 676 | P32927 | Espacenet |
1 to 10 of 146
See all 146 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| CIBINETIDE | CHEMBL3545305 | Innate repair receptor agonist | AGONIST | ChEMBL |
| MAVRILIMUMAB | CHEMBL1743039 | Granulocyte-macrophage colony-stimulating factor receptor antagonist | ANTAGONIST | ChEMBL |
| SARGRAMOSTIM | CHEMBL1201670 | Granulocyte-macrophage colony-stimulating factor receptor agonist | AGONIST | ChEMBL |
Trials451
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07537400 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT07437963 | SARGRAMOSTIM | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT07342322 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT07090538 | SARGRAMOSTIM | EARLY_PHASE1 | ClinicalTrials.gov | |
| NCT07085338 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT07078604 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT06989333 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov | |
| NCT06799026 | SARGRAMOSTIM | PHASE1 | ClinicalTrials.gov | |
| NCT06608303 | SARGRAMOSTIM | ClinicalTrials.gov | ||
| NCT06528496 | SARGRAMOSTIM | PHASE2 | ClinicalTrials.gov |
1 to 10 of 451
See all 451 trialsNIH grants1,415
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CSF2RB papers | Newest fiscal year |
|---|---|---|---|
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P01CA066996 | Development of Novel Therapeutic Strategies in Human Leukemias | 4 | 2025 |
| R01AI051321 | Structure-based engineering of immune cytokine signaling | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 3 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 3 | 2025 |
| R01DE031206 | Trained innate immunity and periodontitis-associated comorbidities | 3 | 2025 |
| R01HL107653 | Cholesterol efflux, CHIP and inflammasome activation | 3 | 2025 |
1 to 10 of 1,415Source NIH's project files
See all 1,415 nih grantsPapers1,845
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Combining co-expression analysis and machine learning to explore the diagnostic value of complement and coagulation cascade-related genes in asthma and the functional role of SERPINB2. | Brief Funct Genomics | 2026 | 42647769 | PubTator, text mining | PubMed |
| Bioinformatics analysis reveals shared gene signatures and molecular mechanisms between periodontitis and rheumatoid arthritis in the context of aging. | Acta Odontol Scand | 2026 | 42627218 | PubTator, text mining | PubMed |
| Clinical value of serum osteocalcin (N-MID) combined with thyroid transcription factor-1 for predicting bone metastasis of lung cancer. | Am J Cancer Res | 2026 | 42597206 | PubTator, text mining | PubMed |
| Peripheral Immune Reprogramming Characterizes a Low C-Peptide Subgroup of Type 2 Diabetes: Transcriptomic Profiling of Peripheral Blood Mononuclear Cells and Systemic Inflammation. | J Inflamm Res | 2026 | 42438590 | PubTator, text mining | PubMed |
| Modeling stimulus-induced stress responses in microglia-like cells using a commercial iPSC-dCas9-KRAB line. | Stem Cell Res | 2026 | 42214129 | PubTator, text mining | PubMed |
| The Kidney-immune Axis: How Erythropoietin Regulates Tolerance and Rejection. | Transplantation | 2026 | 42165263 | PubTator, text mining | PubMed |
| Advancing lupus nephritis research through multi-omics and predictive modeling. | Innate Immun | 2026 | 42041246 | PubTator, text mining | PubMed |
| Discriminating nodular pulmonary alveolar proteinosis from lung adenocarcinoma with radiomic model and multimodal model. | Ther Adv Respir Dis | 2026 | 41905780 | PubTator, text mining | PubMed |
| Immune cell clustering identifies a CD163⁺/CSF1R⁺ macrophage and neutrophil-enriched phenotype with distinct biological signatures and poor prognosis in angiosarcoma. | Oncoimmunology | 2026 | 41870007 | PubTator, text mining | PubMed |
| Preclinical advances and mechanistic insights of CAR-T therapy for acute myeloid leukemia: from target iteration to microenvironment regulation. | Ann Med | 2026 | 41800605 | PubTator, text mining | PubMed |
1 to 10 of 1,845
See all 1,845 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1439
GET https://conductscience.org/api/genes/v1/1439/patents?page=2