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Gene · 1439

CSF2RB: colony stimulating factor 2 receptor subunit beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CSF2RB: colony stimulating factor 2 receptor subunit beta. Genes, record 1439. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1439

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Gene

Symbol
CSF2RB
HGNC
Name
colony stimulating factor 2 receptor subunit beta
HGNC
NCBI Gene ID
1439
NCBI Gene
HGNC ID
HGNC:2436
HGNC
Ensembl
ENSG00000100368
NCBI Gene
Aliases
CD131, CDw131, IL3RB, IL5RB, SMDP5, betaGMR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P32927Cytokine receptor common subunit beta89710Ensembl, GeneID, HGNC

Source UniProt

Patents146

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4795064 A12026-08-267P32927Espacenet
JP 2026510989 A2026-04-1070P32927Espacenet
EP 4705273 A22026-03-11309P32927Espacenet
JP 2026027383 A2026-02-1826P32927Espacenet
JP 2026004568 A2026-01-1441929P32927Espacenet
JP 2026000906 A2026-01-06100P32927Espacenet
JP 2025172069 A2025-11-20135P32927Espacenet
EP 4650780 A22025-11-1911764P32927Espacenet
EP 4641201 A22025-10-2912495P32927Espacenet
EP 4641202 A22025-10-29676P32927Espacenet

1 to 10 of 146

See all 146 patents

Drugs3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CIBINETIDECHEMBL3545305Innate repair receptor agonistAGONISTChEMBL
MAVRILIMUMABCHEMBL1743039Granulocyte-macrophage colony-stimulating factor receptor antagonistANTAGONISTChEMBL
SARGRAMOSTIMCHEMBL1201670Granulocyte-macrophage colony-stimulating factor receptor agonistAGONISTChEMBL

Trials451

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07537400SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT07437963SARGRAMOSTIMPHASE1/PHASE2ClinicalTrials.gov
NCT07342322SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT07090538SARGRAMOSTIMEARLY_PHASE1ClinicalTrials.gov
NCT07085338SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT07078604SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT06989333SARGRAMOSTIMPHASE2ClinicalTrials.gov
NCT06799026SARGRAMOSTIMPHASE1ClinicalTrials.gov
NCT06608303SARGRAMOSTIMClinicalTrials.gov
NCT06528496SARGRAMOSTIMPHASE2ClinicalTrials.gov

1 to 10 of 451

See all 451 trials

NIH grants1,415

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCSF2RB papersNewest fiscal year
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease72025
P30CA008748Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant62025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias42025
R01AI051321Structure-based engineering of immune cytokine signaling42025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA054174Mays Cancer Center at UT Health SA32025
P30ES006694Southwest Environmental Health Sciences Center32025
R01DE031206Trained innate immunity and periodontitis-associated comorbidities32025
R01HL107653Cholesterol efflux, CHIP and inflammasome activation32025

1 to 10 of 1,415Source NIH's project files

See all 1,415 nih grants

Papers1,845

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Combining co-expression analysis and machine learning to explore the diagnostic value of complement and coagulation cascade-related genes in asthma and the functional role of SERPINB2.Brief Funct Genomics202642647769PubTator, text miningPubMed
Bioinformatics analysis reveals shared gene signatures and molecular mechanisms between periodontitis and rheumatoid arthritis in the context of aging.Acta Odontol Scand202642627218PubTator, text miningPubMed
Clinical value of serum osteocalcin (N-MID) combined with thyroid transcription factor-1 for predicting bone metastasis of lung cancer.Am J Cancer Res202642597206PubTator, text miningPubMed
Peripheral Immune Reprogramming Characterizes a Low C-Peptide Subgroup of Type 2 Diabetes: Transcriptomic Profiling of Peripheral Blood Mononuclear Cells and Systemic Inflammation.J Inflamm Res202642438590PubTator, text miningPubMed
Modeling stimulus-induced stress responses in microglia-like cells using a commercial iPSC-dCas9-KRAB line.Stem Cell Res202642214129PubTator, text miningPubMed
The Kidney-immune Axis: How Erythropoietin Regulates Tolerance and Rejection.Transplantation202642165263PubTator, text miningPubMed
Advancing lupus nephritis research through multi-omics and predictive modeling.Innate Immun202642041246PubTator, text miningPubMed
Discriminating nodular pulmonary alveolar proteinosis from lung adenocarcinoma with radiomic model and multimodal model.Ther Adv Respir Dis202641905780PubTator, text miningPubMed
Immune cell clustering identifies a CD163⁺/CSF1R⁺ macrophage and neutrophil-enriched phenotype with distinct biological signatures and poor prognosis in angiosarcoma.Oncoimmunology202641870007PubTator, text miningPubMed
Preclinical advances and mechanistic insights of CAR-T therapy for acute myeloid leukemia: from target iteration to microenvironment regulation.Ann Med202641800605PubTator, text miningPubMed

1 to 10 of 1,845

See all 1,845 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1439

GET https://conductscience.org/api/genes/v1/1439/patents?page=2