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Gene · 1441

CSF3R: colony stimulating factor 3 receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CSF3R: colony stimulating factor 3 receptor. Genes, record 1441. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1441

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Gene

Symbol
CSF3R
HGNC
Name
colony stimulating factor 3 receptor
HGNC
NCBI Gene ID
1441
NCBI Gene
HGNC ID
HGNC:2439
HGNC
Ensembl
ENSG00000119535
NCBI Gene
Aliases
CD114, G-CSF-R, GCSFR, SCN7
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99062Granulocyte colony-stimulating factor receptor8361Ensembl, GeneID, HGNC

Source UniProt

Patents123

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4739706 A12026-05-1316Q99062Espacenet
EP 4727571 A22026-04-22105Q99062Espacenet
JP 2026004568 A2026-01-1441935Q99062Espacenet
JP 2026004568 A2026-01-1441938Q99062Espacenet
JP 2026004568 A2026-01-1441939Q99062Espacenet
EP 4650780 A22025-11-198063Q99062Espacenet
EP 4641201 A22025-10-298174Q99062Espacenet
EP 4633648 A12025-10-2236Q99062Espacenet
JP 2025147176 A2025-10-0616656Q99062Espacenet
JP 2025147176 A2025-10-0616721Q99062Espacenet

1 to 10 of 123

See all 123 patents

Drugs10

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ANUMIGILIMABCHEMBL4650461Granulocyte colony stimulating factor receptor antagonistANTAGONISTChEMBL
BALUGRASTIMCHEMBL2108572Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL
EFBEMALENOGRASTIM ALFACHEMBL4297950Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL
EFLAPEGRASTIMCHEMBL3833384Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL
FILGRASTIMCHEMBL1201567Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL
LENOGRASTIMCHEMBL2109128Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL
LIPEGFILGRASTIMCHEMBL4594230Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL
PEGFILGRASTIMCHEMBL1201568Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL
PEGTEOGRASTIMCHEMBL4297800Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL
REGRAMOSTIMCHEMBL2107881Granulocyte colony stimulating factor receptor agonistAGONISTChEMBL

Trials1,643

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604233FILGRASTIMPHASE1/PHASE2ClinicalTrials.gov
NCT07585136FILGRASTIMPHASE1ClinicalTrials.gov
NCT07541755FILGRASTIMPHASE3ClinicalTrials.gov
NCT07541755PEGFILGRASTIMPHASE3ClinicalTrials.gov
NCT07541755LENOGRASTIMPHASE3ClinicalTrials.gov
NCT07537400REGRAMOSTIMPHASE2ClinicalTrials.gov
NCT07514936FILGRASTIMPHASE3ClinicalTrials.gov
NCT07514936PEGFILGRASTIMPHASE3ClinicalTrials.gov
NCT07514936LENOGRASTIMPHASE3ClinicalTrials.gov
NCT07514832FILGRASTIMPHASE2ClinicalTrials.gov

1 to 10 of 1,643

See all 1,643 trials

NIH grants1,645

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCSF3R papersNewest fiscal year
P30CA016672Cancer Center Support Grant172025
P30CA008748Cancer Center Support Grant152025
P30CA016058Cancer Center Support Grant102025
U54CA224019Architecture and Trajectory of Acquired Resistance to Therapy in AML92025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias72025
UL1TR001863Yale Clinical and Translational Science Award72025
P30CA021765Cancer Center Support Grant (CCSG)62025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant52025
P30CA016056Roswell Park Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant52025

1 to 10 of 1,645Source NIH's project files

See all 1,645 nih grants

Papers3,351

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
CIDER: detecting changes in gene regulatory networks that are associated with changes in phenotype.bioRxiv202642818338PubTator, text miningPubMed
CSF3R compound mutations produce a hyperproliferative leukemia driven by overexpression of PIM kinases.Blood202642814612PubTator, text miningPubMed
Serum NGAL and G-CSFR as Predictive and Prognostic Biomarkers for Trastuzumab-Based Therapy in HER2-Positive Gastric Cancer: A Retrospective Study.Cancer Manag Res202642751472PubTator, text miningPubMed
HIF1A+CSF3R+ neutrophils-dominated hypoxic niche induced metabolic reprogramming for neoadjuvant therapy resistance in NSCLC.J Immunother Cancer202642711068PubTator, text miningPubMed
Myeloid/Lymphoid Neoplasm with FGFR1::ZMYM2 Rearrangement Presenting as T-Cell Acute Lymphoblastic Lymphoma with Concurrent Myeloproliferative Neoplasm: A Case Report.Hematol Rep202642645795PubTator, text miningPubMed
Chronic Neutrophilic Leukemia in a Patient With Multiple Myeloma.Cureus202642634708PubTator, text miningPubMed
Enhanced prognosis of acute myeloid leukaemia patients with dmCEBPAbZIP -inf mutations: Insights from a multicentre Chinese cohort study.Br J Haematol202642629624PubTator, text miningPubMed
Quizartinib Resistance Mutations and Treatment Outcomes in Relapsed or Refractory FLT3-ITD-Positive AML.Cancer Sci202642584468PubTator, text miningPubMed
Longitudinal Molecular Characterization of a Rare TPM3::PDGFRB-Rearranged Myeloid/Lymphoid Neoplasm With Late CNL-Like Neutrophilic Evolution.Eur J Haematol202642549531PubTator, text miningPubMed
CCAAT/enhancer-binding protein alpha basic leucine zipper in-frame insertion/deletion (CEBPA bZIP-InDel-inf) defines a favourable-prognosis subgroup in CEBPA-mutated acute myeloid leukaemia.Br J Haematol202642490742PubTator, text miningPubMed

1 to 10 of 3,351

See all 3,351 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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