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Gene · 144455

E2F7: E2F transcription factor 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. E2F7: E2F transcription factor 7. Genes, record 144455. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/144455

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Gene

Symbol
E2F7
HGNC
Name
E2F transcription factor 7
HGNC
NCBI Gene ID
144455
NCBI Gene
HGNC ID
HGNC:23820
HGNC
Ensembl
ENSG00000165891
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96AV8Transcription factor E2F79110Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444620Q96AV8Espacenet
EP 4640849 A22025-10-29774Q96AV8Espacenet
EP 4641201 A22025-10-295093Q96AV8Espacenet
EP 4641202 A22025-10-294968Q96AV8Espacenet
JP 2025147176 A2025-10-0614910Q96AV8Espacenet
JP 2025519096 A2025-06-24774Q96AV8Espacenet
JP 2025517969 A2025-06-125093Q96AV8Espacenet
JP 2025028160 A2025-02-2814910Q96AV8Espacenet
KR 1020250017231 A2025-02-044968Q96AV8Espacenet
KR 1020250010750 A2025-01-2114910Q96AV8Espacenet

1 to 10 of 23

See all 23 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
EDIFOLIGIDECHEMBL2108316E2F inhibitorINHIBITORChEMBL
EDIFOLIGIDE SODIUMCHEMBL2109058E2F inhibitorINHIBITORChEMBL

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants813

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleE2F7 papersNewest fiscal year
P30CA008748Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant82025
P30CA016058Cancer Center Support Grant42025
P30CA016086Cancer Center Support Grant42025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant42025
P30CA013696Cancer Center Support Grant32025
R35GM128855Spindle Assembly Checkpoint Silencing32025
T32CA009109Cancer Research Training Program: From Molecular Mechanisms to Therapeutic Strategies32025
T32CA009171Training Program in Basic Cancer Research32025
P30CA010815Consolidated Basic Cancer Research Program22025

1 to 10 of 813Source NIH's project files

See all 813 nih grants

Papers1,311

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
E2F7 promotes lung adenocarcinoma progression by affecting phosphorylation and stabilization of β-catenin.Chin Med J (Engl)202642754577PubTator, text miningPubMed
Single-Cell Transcriptome of Anaplastic Thyroid Cancer Reveals Immunosuppressive Tumor Microenvironment Remodeling.Cancer Med202642702761PubTator, text miningPubMed
Bioinformatics-driven single-cell sequencing analysis of angiogenesis-related genes in rheumatoid arthritis.Front Immunol202642528732PubTator, text miningPubMed
MicroRNA-195-5p/E2F7 Axis Underlies the Antimicrobial Additive Triclosan-Induced Cytotoxicity in Human Pulmonary Epithelial Cells.J Appl Toxicol202642309715PubTator, text miningPubMed
RNA-Seq Analysis of Human Cumulus Cells Identifies Angiogenic Pathways Associated with Infertility.Cells202642041545PubTator, text miningPubMed
KCTD10 as a selective cancer dependency from transcription-replication conflicts (TRCs).Ageing Cancer Res Treat202642037670PubTator, text miningPubMed
XPO1 inhibitor selinexor suppresses homologous recombination by inhibiting E2F7 nuclear export in acute myeloid leukemia.Hematology202642026967PubTator, text miningPubMed
Genome-wide Mapping of Histone Modifications and Transcription Factor Binding Sites in Neuroendocrine Small Cell Lung Cancer Cell Lines Using CUT&RUN.J Vis Exp202642008506PubTator, text miningPubMed
Correlation between E2F7 overexpression and immune infiltration in lung adenocarcinoma.Discov Oncol202642001349PubTator, text miningPubMed
Novel Therapies Calls for Predictive Biomarkers: E2F7 in the Era of Perioperative S-1 for Pancreatic Cancer.Ann Surg Oncol202641995962PubTator, text miningPubMed

1 to 10 of 1,311

See all 1,311 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/144455

GET https://conductscience.org/api/genes/v1/144455/patents?page=2