ConductScience.org, home

Library / Genes

TICAM1: TIR domain containing adaptor molecule 1

1 protein, 36 patents, 0 drugs, 0 trials, 4,318 NIH grants and 7,207 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTICAM1HGNC
NameTIR domain containing adaptor molecule 1HGNC
NCBI Gene ID148022NCBI Gene
HGNC IDHGNC:18348HGNC
EnsemblENSG00000127666NCBI Gene
AliasesIIAE6, MGC35334, MyD88-3, PRVTIRB, TICAM-1, TRIFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q8IUC6TIR domain-containing adapter molecule 17128Ensembl, GeneID, HGNCUniProt

Patents 36

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4791413 A22026-08-19168Q8IUC6Espacenet
JP 2026004568 A2026-01-1467236Q8IUC6Espacenet
JP 2024525475 A2024-07-1213Q8IUC6Espacenet
US 11944645 B22024-04-0227Q8IUC6Espacenet
JP 2024512669 A2024-03-1914Q8IUC6Espacenet
KR 1020240026507 A2024-02-282Q8IUC6Espacenet
KR 1020230165276 A2023-12-052Q8IUC6Espacenet
US 11446398 B22022-09-2089180Q8IUC6Espacenet
JP 2022524081 A2022-04-27192151Q8IUC6Espacenet
US 11078247 B22021-08-0311561Q8IUC6Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4318

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK034854Integrated Epithelial and Muscosal Biology202,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success192,025NIH's project files
R01AI124346Innate immune signaling and stress response162,025NIH's project files
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation152,025NIH's project files
P01CA019014Viral Oncogenesis, Latency, and Replication112,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital112,025NIH's project files
R35CA253095Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancer112,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award112,025NIH's project files
P30CA016672Cancer Center Support Grant102,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)102,025NIH's project files

Papers 7207

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822730PubTator, text miningPubMed
42820461PubTator, text miningPubMed
42816628PubTator, text miningPubMed
42805066PubTator, text miningPubMed
42800308PubTator, text miningPubMed
42774487PubTator, text miningPubMed
42732194PubTator, text miningPubMed
42718889PubTator, text miningPubMed
42635620PubTator, text miningPubMed
42614396PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license