Gene · 1487
CTBP1: C-terminal binding protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CTBP1: C-terminal binding protein 1. Genes, record 1487. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1487
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13363 | C-terminal-binding protein 1 | 440 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents48
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12540940 B2 | 2026-02-03 | 29 | Q13363 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3032 | Q13363 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3032 | Q13363 | Espacenet |
| EP 4463571 A1 | 2024-11-20 | 202 | Q13363 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 5678 | Q13363 | Espacenet |
| JP 2024509935 A | 2024-03-05 | 99 | Q13363 | Espacenet |
| JP 2024507735 A | 2024-02-21 | 120 | Q13363 | Espacenet |
| JP 2024506869 A | 2024-02-15 | 88 | Q13363 | Espacenet |
| JP 2024506869 A | 2024-02-15 | 89 | Q13363 | Espacenet |
| JP 2024501437 A | 2024-01-12 | 63 | Q13363 | Espacenet |
1 to 10 of 48
See all 48 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,062
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CTBP1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| R01HL056687 | Mechanisms of Maladaptation in Heart Failure | 10 | 2025 |
| R01AG055357 | Dysregulation of Cav1.2 by beta amyloid peptide | 7 | 2025 |
| R01HL016037 | Molecular Regulation of Cardiovascular 7 TM Receptors | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016059 | Massey Cancer Center - Cancer Center Support Grant | 5 | 2025 |
| P42ES010356 | Duke University Superfund Research Center - Developmental Co-Exposures: Mechanisms, Outcomes, and Remediation | 5 | 2025 |
| R01DK073368 | Mechanisms of Compartmentalized cAMP Signaling | 5 | 2025 |
| R35GM133521 | Investigation of a Newly Discovered Organelle-Based Signaling Paradigm | 5 | 2025 |
| R37GM058615 | Mechanisms and Physiology of COPI Transport | 5 | 2025 |
1 to 10 of 2,062Source NIH's project files
See all 2,062 nih grantsPapers2,891
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Synergistic Variants in C-terminal Binding Protein 1 and Alkaline Phosphatase Lead to Mandibular Hypoplasia Through Impaired Wnt Signaling: An Oligogenic Model. | bioRxiv | 2026 | 42780217 | PubTator, text mining | PubMed |
| Floppy baby syndrome as the first presentation of HADDTS associated with CTBP1 mutation. | Folia Neuropathol | 2026 | 42704868 | PubTator, text mining | PubMed |
| Beyond β-Adrenergic Receptor Brake: Compartment-Selective GRK2 Programs from Heart Failure to Cardio-Oncology. | Kinases Phosphatases | 2026 | 42614945 | PubTator, text mining | PubMed |
| ZEB2 SUMOylation in Cardiac Fibroblast Drives Post-Infarction Cardiac Remodeling through CtBP1-Associated repression of Nr4a1. | iScience | 2026 | 42602983 | PubTator, text mining | PubMed |
| Delineating the CTBP1-Related Phenotypic Spectrum: A Review of HADDTS and Atypical Variants. | Int J Mol Sci | 2026 | 42589715 | PubTator, text mining | PubMed |
| Targeting the CTBP1-CETP axis overcomes ferroptosis resistance in non-small cell lung cancer by altering lipid accumulation. | Clin Transl Med | 2026 | 42515937 | PubTator, text mining | PubMed |
| Molecular mechanism of CtBP1-S/BARS-driven membrane fission and its cellular control by metabolic ligands. | Sci Adv | 2026 | 42497255 | PubTator, text mining | PubMed |
| Methylation patterns linked to blood pressure in people with HIV exposed to antiretroviral therapy reveal neurovascular and immune pathways. | AIDS | 2026 | 42440125 | PubTator, text mining | PubMed |
| Downregulation of long non-coding RNAs PCAT18, HOTAIR, and CTBP1-AS in prostate malignancies. | Mol Biol Rep | 2026 | 42313281 | PubTator, text mining | PubMed |
| A Rare CTBP1-Related Neurodevelopmental Disorder Is Associated with Impaired Mitochondrial Bioenergetics: A Functional Case Report. | Int J Mol Sci | 2026 | 42123581 | PubTator, text mining | PubMed |
1 to 10 of 2,891
See all 2,891 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1487
GET https://conductscience.org/api/genes/v1/1487/patents?page=2