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Gene · 1488

CTBP2: C-terminal binding protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CTBP2: C-terminal binding protein 2. Genes, record 1488. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1488

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Gene

Symbol
CTBP2
HGNC
Name
C-terminal binding protein 2
HGNC
NCBI Gene ID
1488
NCBI Gene
HGNC ID
HGNC:2495
HGNC
Ensembl
ENSG00000175029
NCBI Gene
Aliases
ribeye
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P56545C-terminal-binding protein 24455Ensembl, GeneID, HGNC

Source UniProt

Patents62

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-196368P56545Espacenet
EP 4641201 A22025-10-296123P56545Espacenet
JP 2025517969 A2025-06-126123P56545Espacenet
JP 2025517970 A2025-06-126368P56545Espacenet
JP 2024123008 A2024-09-105683P56545Espacenet
JP 2024123008 A2024-09-105684P56545Espacenet
JP 2024123008 A2024-09-105685P56545Espacenet
JP 2024123008 A2024-09-105687P56545Espacenet
US 11884978 B22024-01-30481P56545Espacenet
US 11446398 B22022-09-2020505P56545Espacenet

1 to 10 of 62

See all 62 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,169

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCTBP2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
P30CA016059Massey Cancer Center - Cancer Center Support Grant72025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30CA008748Cancer Center Support Grant32025
P30CA076292Moffitt Cancer Center Support Grant32025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
P30EY001730Vision Research Core32025
P50CA097186The Pacific Northwest Prostate Cancer SPORE32025
R01DC000188Cochlear synaptopathy in noise-induced and age-related hearing loss: mechanisms and treatments32025
R01EY012857Regulation of Retinal Gap Junctions32025

1 to 10 of 1,169Source NIH's project files

See all 1,169 nih grants

Papers1,330

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Delineating the CTBP1-Related Phenotypic Spectrum: A Review of HADDTS and Atypical Variants.Int J Mol Sci202642589715PubTator, text miningPubMed
Terminal 4q duplication and extended 10q deletion in a preterm infant with linear growth restriction: transcriptomic evidence of disrupted developmental and metabolic pathways.Front Pediatr202642395604PubTator, text miningPubMed
Consistent Metabolomic and Genetic Evidence Supports Acisoga as a Key Contributor to Colorectal Neoplasia Progression.Cancer Epidemiol Biomarkers Prev202642201318PubTator, text miningPubMed
First large-scale screening of Notch biallelic variants implicates novel candidate genes in congenital hypothyroidism.J Clin Endocrinol Metab202642192612PubTator, text miningPubMed
Retraction: CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelialmesenchymal transition in hepatocellular carcinoma.Oncotarget202642030155PubTator, text miningPubMed
Retinal ribbon synapses and the potential functional role of TIAM1: A structural and molecular perspective.Mol Vis202641982461PubTator, text miningPubMed
Functional roles and mechanisms of circRNA-protein interactions in cancer progression and tumor immune regulation.Front Immunol202641756268PubTator, text miningPubMed
Loss of Cathepsin K Impairs Collagen Biogenesis and Enhances Actin Polymerization in Trabecular Meshwork.Invest Ophthalmol Vis Sci202641615370PubTator, text miningPubMed
Synaptic control of retinal ganglion cell survival and axon regeneration.Mol Neurodegener202641606681PubTator, text miningPubMed
Molecular mechanisms and clinical insights of benzo[a]pyrene-related lung adenocarcinoma: New discoveries in multi-scale approaches.Ecotoxicol Environ Saf202641601038PubTator, text miningPubMed

1 to 10 of 1,330

See all 1,330 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1488

GET https://conductscience.org/api/genes/v1/1488/patents?page=2