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CTH: cystathionine gamma-lyase
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Gene · 1491

Papers3,417

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

41 to 60 of 3,417

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TitleJournalYearPMIDFound bySource
Unraveling the role of 3-mercaptopyruvate sulfurtransferase-derived hydrogen sulfide in triple-negative breast cancer chemoresistance.Front Pharmacol202641737561PubTator, text miningPubMed
Enzymes that generate and regulate intracellular persulfides and polysulfides: mechanistic insights and inhibitors.Front Physiol202641736950PubTator, text miningPubMed
Hydrogen sulfide promotes proliferation and regeneration of human cerebral microvascular endothelial cells via the sonic hedgehog signaling pathway.Open Life Sci202641726554PubTator, text miningPubMed
Hydrogen Sulfide: A Multitarget Therapeutic for Neuroinflammation in Neurodegenerative Diseases.Research (Wash D C)202641716845PubTator, text miningPubMed
Gasotransmitters bridging tumor biology and immunity: from pathophysiological insights to therapeutic potential.Front Immunol202641694345PubTator, text miningPubMed
Hydrogen sulfide in ocular physiology and pathology: molecular Mechanisms, therapeutic Paradoxes, and delivery challenges.Mol Biol Rep202641670753PubTator, text miningPubMed
Cystathionine γ-Lyase-Dependent S-Sulfhydration of Smad3: A Novel Target to Alleviate Fibrosis in Systemic Sclerosis.Arthritis Rheumatol202641657106PubTator, text miningPubMed
Protein persulfidation: The missing link in Alzheimer's disease defense mechanisms.Drug Discov Ther202641656099PubTator, text miningPubMed
Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression.J Med Chem202641632838PubTator, text miningPubMed
DPhA-EtOBz-TSC targets cystathionine γ-lyase (CSE) to trigger ferroptosis and inhibit colorectal cancer growth in vitro and in vivo.Eur J Pharmacol202641621574PubTator, text miningPubMed
Combined B-vitamin supplementation on homocysteine and vascular outcomes in coronary heart disease: a meta-analysis.Ann Med202641615824PubTator, text miningPubMed
Anti-Inflammatory Effects of Alpha-Lipoic Acid Modulate Cystathionine-γ-Lyase Expression in RAW 264.7 Macrophages.Int J Mol Sci202641596594PubTator, text miningPubMed
MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review).Int J Mol Med202641574701PubTator, text miningPubMed
Corrigendum to "Hydrogen sulfide in boar reproduction: Cystathionine β-synthase and cystathionine γ-lyase localization in reproductive tissues and sperm across maturation stages" [Theriogenology 252 (2026) 117753].
Theriogenology202641565564PubTator, text miningPubMed
Hydrogen sulfide attenuates PMA-Induced hypertrophy in human cardiomyocytes by modulating gene expression and reducing sulfide methylation.Biochem Pharmacol202641453524PubTator, text miningPubMed
Hydrogen sulfide in boar reproduction: Cystathionine β-synthase and cystathionine γ-lyase localization in reproductive tissues and sperm across maturation stages.Theriogenology202641265009PubTator, text miningPubMed
Aurintricarboxylic acid, an inhibitor of cystathionine γ-lyase, enhances the sensitivity of chemotherapy drugs in TNBC.Transl Oncol202641260197PubTator, text miningPubMed
PGK1 Persulfidation Promotes the Proliferation and Metastasis of Breast Cancer.Antioxid Redox Signal202641250656PubTator, text miningPubMed
Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation.Cell Metab202641175867PubTator, text miningPubMed
Nano-piezoelectric BaTiO3 activate water to overcome pH limitations: A novel oxidase-mimicking strategy for cystathionine-γ-lyase colorimetric biosensing.Talanta202640857760PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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