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CTNNB1: catenin beta 1

1 protein, 251 patents, 1 drug, 8 trials, 28,782 NIH grants and 119,281 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCTNNB1HGNC
Namecatenin beta 1HGNC
NCBI Gene ID1499NCBI Gene
HGNC IDHGNC:2514HGNC
EnsemblENSG00000168036NCBI Gene
AliasesCTNNB, EVR7, MRD19, NEDSDV, armadillo, beta-cateninNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P35222Catenin beta-178150Ensembl, GeneID, HGNCUniProt

Patents 251

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4802081 A12026-09-091P35222Espacenet
JP 2026500012 A2026-01-0551P35222Espacenet
JP 2025541246 A2025-12-181P35222Espacenet
JP 2025541247 A2025-12-181P35222Espacenet
EP 4650780 A22025-11-196896P35222Espacenet
EP 4641201 A22025-10-296721P35222Espacenet
EP 4633656 A12025-10-221P35222Espacenet
EP 4633657 A12025-10-221P35222Espacenet
EP 4606428 A22025-08-2738P35222Espacenet
KR 1020250109203 A2025-07-1651P35222Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
PRI-724CHEMBL4297813CBP/beta catenin inhibitorINHIBITORChEMBL

Trials 8

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06144086PRI-724PHASE2ClinicalTrials.gov
NCT03620474PRI-724PHASE1/PHASE2ClinicalTrials.gov
NCT02828254PRI-724ClinicalTrials.gov
NCT02413853PRI-724PHASE2ClinicalTrials.gov
NCT02195440PRI-724PHASE1ClinicalTrials.gov
NCT01764477PRI-724PHASE1ClinicalTrials.gov
NCT01606579PRI-724PHASE1/PHASE2ClinicalTrials.gov
NCT01302405PRI-724PHASE1ClinicalTrials.gov

NIH grants 28782

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant6902,025NIH's project files
P30CA008748Cancer Center Support Grant4702,025NIH's project files
P30CA006973Regional Oncology Research Center1392,025NIH's project files
P30CA068485Cancer Center Support Grant1152,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases1142,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-20281012,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center972,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award952,025NIH's project files
P30CA016058Cancer Center Support Grant922,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant872,025NIH's project files

Papers 119281

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826871PubTator, text miningPubMed
42826064PubTator, text miningPubMed
42825350PubTator, text miningPubMed
42825329PubTator, text miningPubMed
42825020PubTator, text miningPubMed
42825015PubTator, text miningPubMed
42824924PubTator, text miningPubMed
42824268PubTator, text miningPubMed
42823848PubTator, text miningPubMed
42823710PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license