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CTSL: cathepsin L

1 protein, 201 patents, 0 drugs, 0 trials, 3,990 NIH grants and 8,838 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCTSLHGNC
Namecathepsin LHGNC
NCBI Gene ID1514NCBI Gene
HGNC IDHGNC:2537HGNC
EnsemblENSG00000135047NCBI Gene
AliasesCATL, CTSL1, FLJ31037, MEPNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P07711Procathepsin L33364Ensembl, GeneID, HGNCUniProt

Patents 201

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-0341P07711Espacenet
EP 4662329 A12025-12-17324P07711Espacenet
EP 4662491 A22025-12-172608P07711Espacenet
EP 4650780 A22025-11-196970P07711Espacenet
JP 2025534299 A2025-10-1539P07711Espacenet
JP 2025147176 A2025-10-063757P07711Espacenet
JP 2025147176 A2025-10-063758P07711Espacenet
JP 2025529142 A2025-09-046061P07711Espacenet
US 12371689 B22025-07-296061P07711Espacenet
JP 2025517970 A2025-06-126970P07711Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3990

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAHL006223The role of the intracellular complement system - the complosome - in Th1 biology152,025NIH's project files
P30CA008748Cancer Center Support Grant102,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award92,025NIH's project files
P30CA022453CANCER CENTER SUPPORT GRANT82,025NIH's project files
R01AI032539Cell Biology of Reovirus Infection82,025NIH's project files
P30CA014051Cancer Center Support (Core) Grant62,025NIH's project files
P30CA016672Cancer Center Support Grant62,025NIH's project files
P30CA068485Cancer Center Support Grant62,025NIH's project files
P30CA091842Cancer Center Support Grant62,025NIH's project files
P30EY001792P30 Core Grant for Vision Research62,025NIH's project files

Papers 8838

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823448PubTator, text miningPubMed
42815788PubTator, text miningPubMed
42802308PubTator, text miningPubMed
42774043PubTator, text miningPubMed
42763041PubTator, text miningPubMed
42741323PubTator, text miningPubMed
42718669PubTator, text miningPubMed
42710401PubTator, text miningPubMed
42665765PubTator, text miningPubMed
42603358PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license