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Gene · 1525

CXADR: CXADR cell adhesion molecule

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CXADR: CXADR cell adhesion molecule. Genes, record 1525. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1525

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Gene

Symbol
CXADR
HGNC
Name
CXADR cell adhesion molecule
HGNC
NCBI Gene ID
1525
NCBI Gene
HGNC ID
HGNC:2559
HGNC
Ensembl
ENSG00000154639
NCBI Gene
Aliases
CAR, CAR4/6, HCAR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P78310Coxsackievirus and adenovirus receptor36523Ensembl, GeneID, HGNC

Source UniProt

Patents69

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442321P78310Espacenet
EP 4650780 A22025-11-193235P78310Espacenet
US 12458704 B22025-11-0440P78310Espacenet
JP 2025147176 A2025-10-063792P78310Espacenet
JP 2025529142 A2025-09-041158P78310Espacenet
JP 2025529142 A2025-09-046070P78310Espacenet
US 12371689 B22025-07-291158P78310Espacenet
US 12371689 B22025-07-296070P78310Espacenet
JP 2025517970 A2025-06-123235P78310Espacenet
JP 2025028160 A2025-02-283792P78310Espacenet

1 to 10 of 69

See all 69 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,756

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCXADR papersNewest fiscal year
P30CA016672Cancer Center Support Grant122025
P30CA021765Cancer Center Support Grant (CCSG)122025
P30DK054759Precision Medicine Center for Cystic Fibrosis102025
R01EY013124Immunopathogenesis of Adenovirus Keratitis92025
R35GM118041Regulation of xenobiotic receptors PXR and CAR, and CYP3A: implications in drug disposition92025
P30CA013148Comprehensive Cancer Center Support Grant82025
R01EY006855Models for Therapy of Hereditary Retinal Degeneration82025
P30EY001583P30 Core Grant For Vision Research62025
P30EY014104P30 Core Grant for Vision Research62025
R01AI059374Adenoviral Vector-based Pandemic Influenza Vaccine62025

1 to 10 of 1,756Source NIH's project files

See all 1,756 nih grants

Papers2,820

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Secreted frizzled-related protein 2 as a context-dependent extracellular signaling hub in development, tissue remodeling, and disease.Front Cell Dev Biol202642756375PubTator, text miningPubMed
Ad5/52s fiber substitution alters Ad5 tropism, bioavailability, and plasma sensitivity.Mol Ther Adv202642621217PubTator, text miningPubMed
Differential ChAdOx1 and ChAdOx2 transduction efficiency and receptor specificity in human and mouse B cell lines in vitro.Virology202642612258PubTator, text miningPubMed
State-Dependent 3D Enhancer Architecture Resolves a Shared Schizophrenia and Multiple Sclerosis Ketone and Lactate Sensing Logic Gate.bioRxiv202642427667PubTator, text miningPubMed
ZN002: A Novel Natural Product Small Molecule Inhibitor Targets the Coxsackie-Adenovirus Receptor (CAR) to Control Coxsackie B3 Viral Proliferation.Med Chem202642381309PubTator, text miningPubMed
Periodontal health and disease.Sci Rep202641922666PubTator, text miningPubMed
Neonicotinoid pesticides disrupt gingival epithelial barrier function.Toxicol Rep202641891104PubTator, text miningPubMed
Mechanistic insights into CAR-mediated repression of the HNF4α-FABP1 axis and inhibition of HepG2 cell proliferation.Pharmacol Res202641887343PubTator, text miningPubMed
Spatial tumor evolution panorama of ovarian cancer.Cell Rep Med202641850247PubTator, text miningPubMed
Desmin mutations in cardiomyocytes increase susceptibility to coxsackievirus B3 infection by impairing antiviral IFN-β response and upregulating viral receptors expression.Stem Cell Res Ther202641761335PubTator, text miningPubMed

1 to 10 of 2,820

See all 2,820 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1525

GET https://conductscience.org/api/genes/v1/1525/patents?page=2