Gene · 1528
CYB5A: cytochrome b5 type A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CYB5A: cytochrome b5 type A. Genes, record 1528. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1528
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P00167 | Cytochrome b5 | 134 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4752548 A1 | 2026-06-03 | 1 | P00167 | Espacenet |
| EP 4685238 A2 | 2026-01-28 | 48 | P00167 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 42783 | P00167 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6662 | P00167 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1171 | P00167 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1171 | P00167 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6662 | P00167 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 26974 | P00167 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 26974 | P00167 | Espacenet |
| JP 2023554542 A | 2023-12-27 | 53 | P00167 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,255
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CYB5A papers | Newest fiscal year |
|---|---|---|---|
| R01GM086596 | Activation of androgen biosynthesis and drug metabolism by cytochrome b5 | 27 | 2025 |
| R01DK043140 | Mechanisms Leading to Adrenal Zonation | 12 | 2025 |
| R35GM118145 | Nanoscale Approaches to Understanding Membrane Protein Function | 11 | 2025 |
| P30DK089503 | Michigan Nutrition Obesity Research Center | 6 | 2025 |
| T32ES007028 | Training Program in Environmental Toxicology | 6 | 2025 |
| P30ES007033 | University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment | 5 | 2025 |
| R01HL098032 | Omics, mice and men: Development of precision transfusion medicine | 5 | 2025 |
| T32ES007015 | Molecular & Environmental Toxicology Predoctoral Training Program | 5 | 2025 |
| T32OD010423 | Comparative Biomedical Sciences Training Program | 5 | 2025 |
| P30DK026743 | UCSF Liver Center | 4 | 2025 |
1 to 10 of 1,255Source NIH's project files
See all 1,255 nih grantsPapers2,882
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Familial 46,XY disorder of sex development due to a novel CYB5A variant: a rare cause of isolated 17,20-lyase deficiency. | JCEM Case Rep | 2026 | 42824631 | PubTator, text mining | PubMed |
| Submicellar aggregates of deoxycholate and glycodeoxycholate suppress in vitro CYP3A oxidation via membrane perturbation. | Drug Metab Dispos | 2026 | 42822376 | PubTator, text mining | PubMed |
| Divergence of the CYB5R3-mARC1 Redox Axis Across the Human MASLD-to-Hepatocellular-Carcinoma Continuum: An Exploratory Analysis of Liver-Biopsy and Tumor Cohorts. | Int J Mol Sci | 2026 | 42737704 | PubTator, text mining | PubMed |
| Enhancing the activity of the bifunctional membrane Δ12-hydroxylase/desaturase CpFAH12: Key insights from redox partner interactions and electron transfer pathways. | Int J Biol Macromol | 2026 | 42575354 | PubTator, text mining | PubMed |
| High-level expression of full-length human CYP2E1 in Escherichia coli: Comparison of full-length human CYP2E1 to truncated counterpart shows enhanced association with redox partners. | Drug Metab Dispos | 2026 | 42398471 | PubTator, text mining | PubMed |
| Novel Perspective for Prognostic Stratification and Personalized Therapy in Breast Cancer Patients: Development of Cancer Stem Cells and Metabolism-Associated Prognostic Model. | Int J Womens Health | 2026 | 42358344 | PubTator, text mining | PubMed |
| Free Radical Formation in the Reactions of Redox-Active Drugs and Xenobiotics with Mitochondrial Flavoenzymes. | Biomolecules | 2026 | 42352277 | PubTator, text mining | PubMed |
| Photothermal Conversion and Temperature Elevation by a Minimal Heme Protein. | J Phys Chem B | 2026 | 42343696 | PubTator, text mining | PubMed |
| Integrated Bulk and Single-Cell Transcriptomic Analysis Reveals Xenobiotic Metabolism Genes Drive Progression From Liver Cirrhosis to Hepatocellular Carcinoma. | Hum Mutat | 2026 | 42136961 | PubTator, text mining | PubMed |
| Development and Validation of a Quantitative LC-MS/MS Method for Measuring CYP4V2 Enzyme Activity via 12-Hydroxylauric Acid in rAAV-hCYP4V2 Gene Therapy Products. | Molecules | 2026 | 42123783 | PubTator, text mining | PubMed |
1 to 10 of 2,882
See all 2,882 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1528
GET https://conductscience.org/api/genes/v1/1528/patents?page=2