Gene · 1535
CYBA: cytochrome b-245 alpha chain
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CYBA: cytochrome b-245 alpha chain. Genes, record 1535. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1535
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P13498 | Cytochrome b-245 light chain | 195 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents36
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 42762 | P13498 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1925 | P13498 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1175 | P13498 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1175 | P13498 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1925 | P13498 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 21686 | P13498 | Espacenet |
| US 11408034 B2 | 2022-08-09 | 379 | P13498 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 27 | P13498 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 124657 | P13498 | Espacenet |
| JP 2022511502 A | 2022-01-31 | 98 | P13498 | Espacenet |
1 to 10 of 36
See all 36 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,170
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CYBA papers | Newest fiscal year |
|---|---|---|---|
| ZIAAI000646 | Transgenic Animal Models Of Human Immune Defects | 25 | 2025 |
| ZIAAI000644 | Gene Therapy and Hematopoietic Stem Cell Research to Treat Inherited Primary Immune Deficiencies | 17 | 2025 |
| ZIAAI000645 | Development and Clinical Application of Gene and Cell therapies for Patients with Immune Deficiencies | 17 | 2025 |
| ZIABC010677 | NADPH Oxidases as Novel Targets for Cancer Therapy | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 5 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 5 | 2025 |
| R01EY015130 | Mechanisms of Angiogenesis in ROP | 5 | 2025 |
| R01EY017011 | Endothelial Transmigration in Neovascular Age-related Macular Degeneration | 5 | 2025 |
| ZIAAI000989 | Development and conduct of allogeneic stem cell transplant and autologous stem cell gene therapy for inherited immune deficiencies | 5 | 2025 |
1 to 10 of 2,170Source NIH's project files
See all 2,170 nih grantsPapers3,801
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| SPTLC2-driven sphingolipid reprogramming of neutrophils impairs anti-tumour immunity and drives liver cancer progression. | Oncogene | 2026 | 42806133 | PubTator, text mining | PubMed |
| Retraction: Decorin inhibits glucose-induced lens epithelial cell apoptosis via suppressing p22phox-p38 MAPK signaling pathway. | PLoS One | 2026 | 42784538 | PubTator, text mining | PubMed |
| Human inborn errors of the phagocyte respiratory burst: Chronic granulomatous disease and beyond. | J Hum Immun | 2026 | 42758005 | PubTator, text mining | PubMed |
| Integrated Transcriptomic and Machine-Learning Analyses Identify Shared Na+ Overload-Related Gene Signatures in Inflammatory Bowel Disease and Ankylosing Spondylitis. | Genes (Basel) | 2026 | 42650131 | PubTator, text mining | PubMed |
| Targeting CYBA inhibits hepatic metastasis of pancreatic cancer through AKT/MLC2 pathway. | Acta Pharmacol Sin | 2026 | 42624909 | PubTator, text mining | PubMed |
| Pharmacogenomic variation and chemotherapy-related toxicity profiles in pediatric patients with cancer in Tanzania: a cross-sectional study. | Front Pharmacol | 2026 | 42548792 | PubTator, text mining | PubMed |
| Chronic granulomatous disease secondary to a rare compound heterozygote mutation in an adolescent cured by hematopoietic stem cell transplantation: a case report. | Front Pediatr | 2026 | 42523956 | PubTator, text mining | PubMed |
| Correction: Decorin inhibits glucose-induced lens epithelial cell apoptosis via suppressing p22phox-p38 MAPK signaling pathway. | PLoS One | 2026 | 42519998 | PubTator, text mining | PubMed |
| A Multilevel Redox-Based Prognostic Model for Asthma Severity: From Genotype to Serum Biomarkers. | Biomedicines | 2026 | 42511983 | PubTator, text mining | PubMed |
| FOXC1: A Key Transcription Factor of VSMC-Derived Foam Cell Formation in Atherosclerotic Plaque Instability. | Kaohsiung J Med Sci | 2026 | 42477884 | PubTator, text mining | PubMed |
1 to 10 of 3,801
See all 3,801 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1535
GET https://conductscience.org/api/genes/v1/1535/patents?page=2