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Gene · 153562

MARVELD2: MARVEL domain containing 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MARVELD2: MARVEL domain containing 2. Genes, record 153562. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/153562

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Gene

Symbol
MARVELD2
HGNC
Name
MARVEL domain containing 2
HGNC
NCBI Gene ID
153562
NCBI Gene
HGNC ID
HGNC:26401
HGNC
Ensembl
ENSG00000152939
NCBI Gene
Aliases
DFNB49, FLJ30532, MARVD2, MRVLDC2, TRIC, Tric
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8N4S9MARVEL domain-containing protein 25583Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452646Q8N4S9Espacenet
EP 4650780 A22025-11-195482Q8N4S9Espacenet
EP 4641201 A22025-10-295094Q8N4S9Espacenet
JP 2025529142 A2025-09-042555Q8N4S9Espacenet
US 12371689 B22025-07-292555Q8N4S9Espacenet
JP 2025517969 A2025-06-125094Q8N4S9Espacenet
JP 2025517970 A2025-06-125482Q8N4S9Espacenet
JP 2025032204 A2025-03-1131227Q8N4S9Espacenet
EP 4461818 A22024-11-1331227Q8N4S9Espacenet
JP 2023058610 A2023-04-2531227Q8N4S9Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,061

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMARVELD2 papersNewest fiscal year
ZIABC010666Cancer Immunotherapy202025
ZIABC010598Human Immune Responses to Tumor Antigens for Cancer Immunotherapy112025
R01GM056433Protein Folding in the Eukaryotic Cytosol102025
R01DK061931Mechanisms and pathophysiologic impact of claudin-2 modulation82025
R01DK068271Therapeutic targeting of protein interactions to reverse MLCK1-mediated intestinal barrier loss and ameliorate disease.82025
ZIABC010661Vaccine and Drug Combination Therapy for Human Cancers82025
P30CA016672Cancer Center Support Grant52025
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)52025
ZIABC010944Strategies for Cancer Immunotherapy Development: Preclinical Studies52025
P30ES001247Environmental Agents as Modulators of Disease Processes42025

1 to 10 of 1,061Source NIH's project files

See all 1,061 nih grants

Papers1,744

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
From protection to progression: How CCT/TRiC shapes therapy-induced senescence in glioblastoma multiforme.Biochim Biophys Acta Mol Basis Dis202742624300PubTator, text miningPubMed
The CCT6A paradigm: biomarker potential and therapeutic challenges in oncology and beyond.Mol Biol Rep202642758405PubTator, text miningPubMed
Differential Modulation of the DR5-JNK-PD-L1 Signaling Axis by TRiC/CCT Subunits CCT7 and CCT2 Shapes Tumor Immune Evasion in Lung Adenocarcinoma.Cells202642738906PubTator, text miningPubMed
CCT8 associates with the MYO10 motor domain and regulates filopodia and breast cancer cell invasion.J Cell Sci202642677351PubTator, text miningPubMed
CCT3 Enhances Lung Adenocarcinoma Progression by Promoting p53 Ubiquitination and Degradation.Medicina (Kaunas)202642654382PubTator, text miningPubMed
Integration of CCT/TRiC assembly, degradation and function: Chaperonin complexity in a cellular context.Cell Stress Chaperones202642628785PubTator, text miningPubMed
Trophoblast Retrieval from the Cervix (TRIC) Across Early Gestation: A Multi-Method Assessment of Extravillous Trophoblast Recovery.Int J Mol Sci202642589299PubTator, text miningPubMed
MSTO1 functions as a TRiC assembly factor linking cytosolic proteostasis to mitochondrial function.bioRxiv202642539026PubTator, text miningPubMed
TRiC-assisted folding of class I HDAC family proteins regulated by distinct co-chaperone and cofactor networks.Sci Adv202642455925PubTator, text miningPubMed
Cell-cell junction gene signatures as subtype-specific prognostic biomarkers in breast cancer.PLoS One202642371976PubTator, text miningPubMed

1 to 10 of 1,744

See all 1,744 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/153562

GET https://conductscience.org/api/genes/v1/153562/patents?page=2