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ADRB2: adrenoceptor beta 2

1 protein, 48 patents, 110 drugs, 2,202 trials, 8,369 NIH grants and 16,648 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolADRB2HGNC
Nameadrenoceptor beta 2HGNC
NCBI Gene ID154NCBI Gene
HGNC IDHGNC:286HGNC
EnsemblENSG00000169252NCBI Gene
AliasesADRB2R, ADRBR, ARB2, B2AR, BAR, BETA2ARNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P07550Beta-2 adrenergic receptor413146Ensembl, GeneID, HGNCUniProt

Patents 48

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436852P07550Espacenet
EP 4640849 A22025-10-29569P07550Espacenet
EP 4641201 A22025-10-293883P07550Espacenet
EP 4641202 A22025-10-29228P07550Espacenet
JP 2025131693 A2025-09-0914P07550Espacenet
JP 2025131693 A2025-09-0917P07550Espacenet
JP 2025529142 A2025-09-04337P07550Espacenet
US 12371689 B22025-07-29337P07550Espacenet
JP 2025519096 A2025-06-24569P07550Espacenet
JP 2025517969 A2025-06-123883P07550Espacenet

Drugs 110

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABEDITEROLCHEMBL3039530Beta-2 adrenergic receptor agonistAGONISTChEMBL
ALBUTEROLCHEMBL714Beta-2 adrenergic receptor agonistAGONISTChEMBL
ALBUTEROL SULFATECHEMBL1441059Beta-2 adrenergic receptor agonistAGONISTChEMBL
ARFORMOTEROLCHEMBL1363Beta-2 adrenergic receptor agonistAGONISTChEMBL
ARFORMOTEROL TARTRATECHEMBL1951071Beta-2 adrenergic receptor agonistAGONISTChEMBL
AZD3199CHEMBL3545103Beta-2 adrenergic receptor agonistAGONISTChEMBL
BAMBUTEROLCHEMBL521589Beta-2 adrenergic receptor agonistAGONISTChEMBL
BAMOSIRANCHEMBL4298113Beta-2 adrenergic receptor mRNA RNAi inhibitorRNAI INHIBITORChEMBL
BATEFENTEROLCHEMBL3039518Beta-2 adrenergic receptor agonistAGONISTChEMBL
BEDORADRINECHEMBL2111083Beta-2 adrenergic receptor agonistAGONISTChEMBL

Trials 2202

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07603596ESMOLOLPHASE1ClinicalTrials.gov
NCT07595796FORMOTEROLClinicalTrials.gov
NCT07577518CARVEDILOLClinicalTrials.gov
NCT07572656LABETALOLClinicalTrials.gov
NCT07560332PROPRANOLOLClinicalTrials.gov
NCT07560332TIMOLOLClinicalTrials.gov
NCT07549906PROPRANOLOLPHASE2ClinicalTrials.gov
NCT07546981FORMOTEROL FUMARATEPHASE3ClinicalTrials.gov
NCT07541378INDACATEROLClinicalTrials.gov
NCT07541378VILANTEROLClinicalTrials.gov

NIH grants 8369

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01HL016037Molecular Regulation of Cardiovascular 7 TM Receptors1122,025NIH's project files
R01HL058506G Protein-Coupled Receptor Regulation in Airway Myocytes382,025NIH's project files
R01DA012864Mechanisms and Cellular Function of Opioid Receptor Endocytosis372,025NIH's project files
R01EY011500Structure-function studies of visual arrestin362,025NIH's project files
P30CA016672Cancer Center Support Grant262,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant232,025NIH's project files
ZIADK031117Development of Drugs Acting at Adenosine Receptors232,025NIH's project files
R01DK073368Mechanisms of Compartmentalized cAMP Signaling192,025NIH's project files
R01MH054137Structure and Function of Dopamine Receptors182,025NIH's project files
T32HL007427SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASES172,025NIH's project files

Papers 16648

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42816609PubTator, text miningPubMed
42800465PubTator, text miningPubMed
42799194PubTator, text miningPubMed
42789144PubTator, text miningPubMed
42770438PubTator, text miningPubMed
42770163PubTator, text miningPubMed
42765498PubTator, text miningPubMed
42753839PubTator, text miningPubMed
42748893PubTator, text miningPubMed
42746671PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license