Gene · 1551
CYP3A7: cytochrome P450 family 3 subfamily A member 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CYP3A7: cytochrome P450 family 3 subfamily A member 7. Genes, record 1551. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1551
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P24462 | Cytochrome P450 3A7 | 503 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents26
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 6042 | P24462 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1193 | P24462 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1193 | P24462 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6042 | P24462 | Espacenet |
| JP 2024128028 A | 2024-09-20 | 7 | P24462 | Espacenet |
| US 11760977 B2 | 2023-09-19 | 7 | P24462 | Espacenet |
| US 11685901 B2 | 2023-06-27 | 7 | P24462 | Espacenet |
| JP 2022153580 A | 2022-10-12 | 7 | P24462 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 22068 | P24462 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 239 | P24462 | Espacenet |
1 to 10 of 26
See all 26 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials513
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07261085 | RITONAVIR | ClinicalTrials.gov | ||
| NCT07072793 | RITONAVIR | 2026-01-12 | ClinicalTrials.gov | |
| NCT06799650 | RITONAVIR | PHASE2 | ClinicalTrials.gov | |
| NCT06735300 | RITONAVIR | ClinicalTrials.gov | ||
| NCT06710990 | RITONAVIR | PHASE1 | ClinicalTrials.gov | |
| NCT06610643 | RITONAVIR | ClinicalTrials.gov | ||
| NCT06428045 | RITONAVIR | PHASE1 | ClinicalTrials.gov | |
| NCT06291831 | RITONAVIR | 2025-08-19 | ClinicalTrials.gov | |
| NCT06139796 | RITONAVIR | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT06016556 | RITONAVIR | 2025-04-29 | ClinicalTrials.gov |
1 to 10 of 513
See all 513 trialsNIH grants803
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CYP3A7 papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 6 | 2025 |
| R01HD081299 | Ontogeny of drug transport | 6 | 2025 |
| R35GM118041 | Regulation of xenobiotic receptors PXR and CAR, and CYP3A: implications in drug disposition | 6 | 2025 |
| T32GM008425 | Indiana University Comprehensive Training in Clinical Pharmacology | 6 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 5 | 2025 |
| R35GM140845 | Expression genetics of pharmacogenes | 5 | 2025 |
| UM1AI068632 | IMPAACT Leadership Group | 5 | 2025 |
| ZIABC005562 | Xenobiotic receptors | 5 | 2025 |
| P30DK026743 | UCSF Liver Center | 4 | 2025 |
| P30ES007033 | University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment | 4 | 2025 |
1 to 10 of 803Source NIH's project files
See all 803 nih grantsPapers1,325
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Submicellar aggregates of deoxycholate and glycodeoxycholate suppress in vitro CYP3A oxidation via membrane perturbation. | Drug Metab Dispos | 2026 | 42822376 | PubTator, text mining | PubMed |
| Role of CYP3A5 and CYP3A4 in the metabolism and toxicity of 10-hydroxyl mesaconitine, a new potential toxicity marker of Radix Aconiti Lateralis Preparata (Fuzi), in vitro and in vivo. | Drug Metab Dispos | 2026 | 42456275 | PubTator, text mining | PubMed |
| Contribution of cytochrome P450-mediated metabolism to clavulanic acid-induced cytotoxicity in TK6-derived cytochrome P450-overexpressing cell lines. | Sci Rep | 2026 | 42449129 | PubTator, text mining | PubMed |
| Hyocholic acids: Third bile acids for neonatal health. | Trends Mol Med | 2026 | 42399159 | PubTator, text mining | PubMed |
| A CYP3A7 metabolically competent human induced pluripotent stem cell-derived hepatocyte-like cell (hHLC3A7) model for drug safety assessment in the newborn. | Drug Metab Dispos | 2026 | 42224858 | PubTator, text mining | PubMed |
| Hyocholic acids shape neonatal immune tolerance and microbiota assembly. | Cell Metab | 2026 | 42167251 | PubTator, text mining | PubMed |
| Pregnane X Receptor Regulates Human Endocrine System by Inducing Sex Hormone-Binding Globulin Expression. | Basic Clin Pharmacol Toxicol | 2026 | 41789448 | PubTator, text mining | PubMed |
| A cell atlas of multiple liver organoids and the fetal liver based on scRNA-seq. | iScience | 2026 | 41736863 | PubTator, text mining | PubMed |
| Genetic Modulation of Mercury Exposure on Perinatal and Birth Outcomes: A Systematic Review and Meta-Analysis of Gene-Environment Interactions. | J Xenobiot | 2026 | 41718271 | PubTator, text mining | PubMed |
| Altered gene expression and activity of human placental drug-metabolizing cytochrome P450 enzymes across gestation. | Biochem Pharmacol | 2026 | 41679666 | PubTator, text mining | PubMed |
1 to 10 of 1,325
See all 1,325 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1551
GET https://conductscience.org/api/genes/v1/1551/patents?page=2