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CYP2C8: cytochrome P450 family 2 subfamily C member 8

1 protein, 30 patents, 0 drugs, 0 trials, 1,952 NIH grants and 4,965 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCYP2C8HGNC
Namecytochrome P450 family 2 subfamily C member 8HGNC
NCBI Gene ID1558NCBI Gene
HGNC IDHGNC:2622HGNC
EnsemblENSG00000138115NCBI Gene
AliasesCPC8, CYP2C8DM, CYPIIC8, MP-12/MP-20NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P10632Cytochrome P450 2C84905Ensembl, GeneID, HGNCUniProt

Patents 30

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4685238 A22026-01-2832P10632Espacenet
JP 2026004568 A2026-01-1442865P10632Espacenet
EP 4650780 A22025-11-198924P10632Espacenet
EP 4641201 A22025-10-299172P10632Espacenet
JP 2025147176 A2025-10-063871P10632Espacenet
JP 2025529142 A2025-09-046097P10632Espacenet
US 12371689 B22025-07-296097P10632Espacenet
JP 2025517969 A2025-06-129172P10632Espacenet
JP 2025517970 A2025-06-128924P10632Espacenet
JP 2025028160 A2025-02-283871P10632Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 1952

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAES025034Characterization And Functional Significance Of P450 Arachidonate Epoxygenases232,025NIH's project files
P30CA008748Cancer Center Support Grant212,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)102,025NIH's project files
P30CA047904Cancer Center Support Grant92,025NIH's project files
P30CA016672Cancer Center Support Grant82,025NIH's project files
P30DK026743UCSF Liver Center72,025NIH's project files
T32GM008425Indiana University Comprehensive Training in Clinical Pharmacology72,025NIH's project files
R35ES030443Bioactive lipids as effectors and indicators of the deleterious effects of environmental exposure on chronic diseases62,025NIH's project files
R35GM143044Interindividual Variability in Drug Metabolism in Ethnically Diverse Populations62,025NIH's project files
T32GM007019Clinical Therapeutics62,025NIH's project files

Papers 4965

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823492PubTator, text miningPubMed
42815442PubTator, text miningPubMed
42763370PubTator, text miningPubMed
42742947PubTator, text miningPubMed
42662256PubTator, text miningPubMed
42612544PubTator, text miningPubMed
42597673PubTator, text miningPubMed
42581437PubTator, text miningPubMed
42561866PubTator, text miningPubMed
42555833PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license