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GRK2: G protein-coupled receptor kinase 2
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Gene · 156

Papers3,264

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 3,264

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TitleJournalYearPMIDFound bySource
EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2-Mediated µ-Opioid Receptor Internalization.Adv Sci (Weinh)202642817043PubTator, text miningPubMed
GRK2-JAK1 binding represses hyperproliferation of fibroblast-like synoviocytes in rheumatoid arthritis by inhibiting STAT3 activation.Biochem Pharmacol202642815591PubTator, text miningPubMed
Molecular Mechanisms of Electroacupuncture-Induced Spinal Microglial Reprogramming in Neuropathic Pain: A Systematic Search-Narrative Review.Brain Sci202642793339PubTator, text miningPubMed
From Traditional Remedy to Evidence-Based Phytotherapeutic Agent: Hedera helix L. in Respiratory Medicine.Plants (Basel)202642739377PubTator, text miningPubMed
Retraction notice to "Paroxetine attenuates doxorubicin-induced cardiotoxicity: Integrated network pharmacology, molecular modeling, and in vivo evidence consistent with modulation of GRK2/iNOS-related pathways" [Toxicol. Appl. Pharmacol. 513 (2026) 117864].
Toxicol Appl Pharmacol202642735829PubTator, text miningPubMed
[The relationship between serum G protein-coupled receptor kinase 2 level and the occurrence of sepsis-associated liver injury].Zhonghua Wei Zhong Bing Ji Jiu Yi Xue202642693972PubTator, text miningPubMed
Beyond β-Adrenergic Receptor Brake: Compartment-Selective GRK2 Programs from Heart Failure to Cardio-Oncology.Kinases Phosphatases202642614945PubTator, text miningPubMed
Recent advances in the development of GRK2 inhibitors: blocking the interaction of GRK2 with its partners.Acta Pharmacol Sin202642410249PubTator, text miningPubMed
Beyond Raf-1 inhibition: RKIP's multifaceted roles in cellular homeostasis.Biochim Biophys Acta Rev Cancer202642323054PubTator, text miningPubMed
Fast pairwise coalescence enables gene-resolution scans for recent selection in diverse human populations.bioRxiv202642239206PubTator, text miningPubMed
Adenosine Receptor Functionality and Desensitization Machinery in a Neuronal Cell Model of Angelman Syndrome.J Dev Biol202642201242PubTator, text miningPubMed
GPCR kinases shape ACKR4 functions via differential C-terminal phosphorylation.Nat Commun202642143096PubTator, text miningPubMed
Functional Characterization of HvGRK2 in Metamorphic Development and 20E-Related Signaling in Heortia vitessoides.Arch Insect Biochem Physiol202642138599PubTator, text miningPubMed
Local GPCR density tips the balance of μ-opioid receptor trafficking.bioRxiv202642124644PubTator, text miningPubMed
Neutrophils exhibit distinct migration phenotypes that are modulated by transendothelial migration.Commun Biol202642049959PubTator, text miningPubMed
Reply to the Letter to the Editor from Chen Xue entitled "Revisiting the GRK2-NOX4 axis in cisplatin-induced nephrotoxicity."Br J Pharmacol202642021466PubTator, text miningPubMed
Proteogenomic decoding of chemotherapy resistance in patients with triple-negative breast cancer.Genome Biol202641975515PubTator, text miningPubMed
Revisiting the GRK2-NOX4 axis in cisplatin-induced nephrotoxicity.Br J Pharmacol202641954008PubTator, text miningPubMed
Beef-Derived Peptides Mediated Desensitization of Bitter Taste Receptor T2R14 Through GPCR Kinase 2.Nutrients202641901075PubTator, text miningPubMed
Analysis of GRK2 aggregation in the pathology of Alzheimer disease in animal models.Cell Rep Med202641895286PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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