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CYP2E1: cytochrome P450 family 2 subfamily E member 1

1 protein, 56 patents, 0 drugs, 0 trials, 3,582 NIH grants and 10,010 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCYP2E1HGNC
Namecytochrome P450 family 2 subfamily E member 1HGNC
NCBI Gene ID1571NCBI Gene
HGNC IDHGNC:2631HGNC
EnsemblENSG00000130649NCBI Gene
AliasesCPE1, CYP2E, P450-J, P450C2ENCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05181Cytochrome P450 2E14936Ensembl, GeneID, HGNCUniProt

Patents 56

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442876P05181Espacenet
JP 2026004568 A2026-01-1442877P05181Espacenet
JP 2025147176 A2025-10-063882P05181Espacenet
JP 2025147176 A2025-10-063883P05181Espacenet
JP 2025529142 A2025-09-046099P05181Espacenet
EP 4594342 A22025-08-06134P05181Espacenet
US 12371689 B22025-07-296099P05181Espacenet
JP 2025028160 A2025-02-283882P05181Espacenet
JP 2025028160 A2025-02-283883P05181Espacenet
KR 1020250010750 A2025-01-213882P05181Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3582

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAAA000036Alcohol Metabolism, Functional Consequences, Apoptosis Signaling Pathways, and Organ Damage342,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility252,025NIH's project files
P50AA011999Southern California Research Center for ALPD and Cirrhosis232,025NIH's project files
ZIABC005562Xenobiotic receptors232,025NIH's project files
P30DK026743UCSF Liver Center202,025NIH's project files
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers202,025NIH's project files
P42ES004705Toxic substances in the environment192,025NIH's project files
P30CA077598Cancer Center Support Grant152,025NIH's project files
P30ES006694Southwest Environmental Health Sciences Center142,025NIH's project files
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment122,025NIH's project files

Papers 10010

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827146PubTator, text miningPubMed
42788347PubTator, text miningPubMed
42765520PubTator, text miningPubMed
42753829PubTator, text miningPubMed
42753303PubTator, text miningPubMed
42720376PubTator, text miningPubMed
42710335PubTator, text miningPubMed
42703538PubTator, text miningPubMed
42682783PubTator, text miningPubMed
42631638PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license