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CYP27B1: cytochrome P450 family 27 subfamily B member 1

1 protein, 20 patents, 0 drugs, 0 trials, 2,103 NIH grants and 4,874 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCYP27B1HGNC
Namecytochrome P450 family 27 subfamily B member 1HGNC
NCBI Gene ID1594NCBI Gene
HGNC IDHGNC:2606HGNC
EnsemblENSG00000111012NCBI Gene
AliasesCP2B, CYP1, CYP1alpha, CYP27B, P450c1, PDDR, VDD1, VDDR, VDDRINCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O1552825-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial5080Ensembl, GeneID, HGNCUniProt

Patents 20

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442908O15528Espacenet
EP 4641202 A22025-10-294368O15528Espacenet
KR 1020250017231 A2025-02-044368O15528Espacenet
US 11446398 B22022-09-2022045O15528Espacenet
JP 2022524081 A2022-04-27125016O15528Espacenet
US 11078247 B22021-08-032811O15528Espacenet
JP 2019054813 A2019-04-11223343O15528Espacenet
JP 2017121241 A2017-07-13223343O15528Espacenet
JP 2015516143 A2015-06-08223343O15528Espacenet
JP 2006516089 A2006-06-225309O15528Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2103

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01AR073004Mechanism of action and function of novel secosteroid 20(OH)D3 in the skin302,025NIH's project files
I01BX004293CYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancer252,025NIH's project files
R01AR040312CD1-restricted T-cell Responses in Skin132,025NIH's project files
R01AI022553Molecular Analysis of Host Immune Response in Leprosy122,025NIH's project files
ZIAES101586Nuclear receptors: action, functions, and roles in disease122,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant82,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant82,025NIH's project files
P30CA013148Comprehensive Cancer Center Support Grant72,025NIH's project files
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment72,025NIH's project files
P42ES013661Iowa Superfund Research Program: Airborne PCBs: Sources, Exposures, Toxicities, Remediation52,025NIH's project files

Papers 4874

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818793PubTator, text miningPubMed
42784771PubTator, text miningPubMed
42783391PubTator, text miningPubMed
42749425PubTator, text miningPubMed
42733725PubTator, text miningPubMed
42712955PubTator, text miningPubMed
42648036PubTator, text miningPubMed
42605157PubTator, text miningPubMed
42604156PubTator, text miningPubMed
42598195PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license