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Gene · 1595

CYP51A1: cytochrome P450 family 51 subfamily A member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CYP51A1: cytochrome P450 family 51 subfamily A member 1. Genes, record 1595. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1595

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Gene

Symbol
CYP51A1
HGNC
Name
cytochrome P450 family 51 subfamily A member 1
HGNC
NCBI Gene ID
1595
NCBI Gene
HGNC ID
HGNC:2649
HGNC
Ensembl
ENSG00000001630
NCBI Gene
Aliases
CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16850Lanosterol 14-alpha demethylase50910Ensembl, GeneID, HGNC

Source UniProt

Patents37

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442943Q16850Espacenet
EP 4650780 A22025-11-198Q16850Espacenet
EP 4641202 A22025-10-291Q16850Espacenet
JP 2025517970 A2025-06-128Q16850Espacenet
KR 1020250017231 A2025-02-041Q16850Espacenet
EP 4463571 A12024-11-20204Q16850Espacenet
US 11446398 B22022-09-2022130Q16850Espacenet
US 11400116 B22022-08-02247Q16850Espacenet
JP 2022524081 A2022-04-27125101Q16850Espacenet
KR 1020210113137 A2021-09-1511Q16850Espacenet

1 to 10 of 37

See all 37 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,049

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCYP51A1 papersNewest fiscal year
P30DK026743UCSF Liver Center52025
P30CA043703Case Comprehensive Cancer Center Support Grant42025
R01GM086596Activation of androgen biosynthesis and drug metabolism by cytochrome b542025
T32AI007281Molecular Microbial Pathogenesis Training Program42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
P30CA008748Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
R01LM012806Predicting Phenotype by Deep Learning Heterogeneous Multi-Omics Data32025
R35GM118145Nanoscale Approaches to Understanding Membrane Protein Function32025

1 to 10 of 1,049Source NIH's project files

See all 1,049 nih grants

Papers2,112

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Coumarin-Based Antifungal Leads: Design, Synthesis, Mechanistic Insights, and Synergistic Activity.Chem Biodivers202642814860PubTator, text miningPubMed
Synthesis, molecular docking and biological activity assessment of novel 1,3,4-oxadiazole derivatives as broad-spectrum antifungal candidates.RSC Adv202642813028PubTator, text miningPubMed
CAFs-mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression.J Pathol202642711289PubTator, text miningPubMed
Linker Engineering of Hybrid Triazole-Thiazolidine Antifungals Identifies a Promising Lead Against Drug-Resistant Candida Species.Pharmaceuticals (Basel)202642653757PubTator, text miningPubMed
Virulence Profiles and Fungicide-Target-Gene Variability in Puccinia graminis f. sp. tritici Populations from Russian Regions.J Fungi (Basel)202642646131PubTator, text miningPubMed
Dual-Targeting, Hybrid Antifungal Agents Targeting Candida albicans-An Overview.Chem Biol Drug Des202642630000PubTator, text miningPubMed
Design, synthesis, molecular modelling and biological evaluation of oxiconazole-based 1,2,3-triazoles as dually acting antifungal and antitumor agents.Sci Rep202642601411PubTator, text miningPubMed
Design and mechanistic evaluation of chalcone-quinoline-triazole hybrids as antifungal CYP51 inhibitors.Med Chem Res202642599305PubTator, text miningPubMed
In Vitro Antifungal Evaluation, GC-MS Profiling, and Molecular Docking of Eruca sativa Oil, Clove Oil, and Fusarium chlamydosporum Extract Against the Dermatophyte Trichophyton interdigitale.Curr Microbiol202642461428PubTator, text miningPubMed
Spatiotemporal Distribution, Mechanisms, and Field Efficacy of Tebuconazole Resistance in Blumeria graminis f. sp. tritici (Bgt) Populations in Hebei, Henan, and Shandong Provinces, China.Plant Dis202642449206PubTator, text miningPubMed

1 to 10 of 2,112

See all 2,112 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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