Gene · 1595
CYP51A1: cytochrome P450 family 51 subfamily A member 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CYP51A1: cytochrome P450 family 51 subfamily A member 1. Genes, record 1595. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1595
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16850 | Lanosterol 14-alpha demethylase | 509 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents37
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 42943 | Q16850 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8 | Q16850 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 1 | Q16850 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8 | Q16850 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 1 | Q16850 | Espacenet |
| EP 4463571 A1 | 2024-11-20 | 204 | Q16850 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 22130 | Q16850 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 247 | Q16850 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 125101 | Q16850 | Espacenet |
| KR 1020210113137 A | 2021-09-15 | 11 | Q16850 | Espacenet |
1 to 10 of 37
See all 37 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,049
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CYP51A1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK026743 | UCSF Liver Center | 5 | 2025 |
| P30CA043703 | Case Comprehensive Cancer Center Support Grant | 4 | 2025 |
| R01GM086596 | Activation of androgen biosynthesis and drug metabolism by cytochrome b5 | 4 | 2025 |
| T32AI007281 | Molecular Microbial Pathogenesis Training Program | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| R01LM012806 | Predicting Phenotype by Deep Learning Heterogeneous Multi-Omics Data | 3 | 2025 |
| R35GM118145 | Nanoscale Approaches to Understanding Membrane Protein Function | 3 | 2025 |
1 to 10 of 1,049Source NIH's project files
See all 1,049 nih grantsPapers2,112
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Coumarin-Based Antifungal Leads: Design, Synthesis, Mechanistic Insights, and Synergistic Activity. | Chem Biodivers | 2026 | 42814860 | PubTator, text mining | PubMed |
| Synthesis, molecular docking and biological activity assessment of novel 1,3,4-oxadiazole derivatives as broad-spectrum antifungal candidates. | RSC Adv | 2026 | 42813028 | PubTator, text mining | PubMed |
| CAFs-mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression. | J Pathol | 2026 | 42711289 | PubTator, text mining | PubMed |
| Linker Engineering of Hybrid Triazole-Thiazolidine Antifungals Identifies a Promising Lead Against Drug-Resistant Candida Species. | Pharmaceuticals (Basel) | 2026 | 42653757 | PubTator, text mining | PubMed |
| Virulence Profiles and Fungicide-Target-Gene Variability in Puccinia graminis f. sp. tritici Populations from Russian Regions. | J Fungi (Basel) | 2026 | 42646131 | PubTator, text mining | PubMed |
| Dual-Targeting, Hybrid Antifungal Agents Targeting Candida albicans-An Overview. | Chem Biol Drug Des | 2026 | 42630000 | PubTator, text mining | PubMed |
| Design, synthesis, molecular modelling and biological evaluation of oxiconazole-based 1,2,3-triazoles as dually acting antifungal and antitumor agents. | Sci Rep | 2026 | 42601411 | PubTator, text mining | PubMed |
| Design and mechanistic evaluation of chalcone-quinoline-triazole hybrids as antifungal CYP51 inhibitors. | Med Chem Res | 2026 | 42599305 | PubTator, text mining | PubMed |
| In Vitro Antifungal Evaluation, GC-MS Profiling, and Molecular Docking of Eruca sativa Oil, Clove Oil, and Fusarium chlamydosporum Extract Against the Dermatophyte Trichophyton interdigitale. | Curr Microbiol | 2026 | 42461428 | PubTator, text mining | PubMed |
| Spatiotemporal Distribution, Mechanisms, and Field Efficacy of Tebuconazole Resistance in Blumeria graminis f. sp. tritici (Bgt) Populations in Hebei, Henan, and Shandong Provinces, China. | Plant Dis | 2026 | 42449206 | PubTator, text mining | PubMed |
1 to 10 of 2,112
See all 2,112 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1595
GET https://conductscience.org/api/genes/v1/1595/patents?page=2