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Gene · 1613

DAPK3: death associated protein kinase 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DAPK3: death associated protein kinase 3. Genes, record 1613. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1613

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Gene

Symbol
DAPK3
HGNC
Name
death associated protein kinase 3
HGNC
NCBI Gene ID
1613
NCBI Gene
HGNC ID
HGNC:2676
HGNC
Ensembl
ENSG00000167657
NCBI Gene
Aliases
DLK, ZIP, ZIPK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O43293Death-associated protein kinase 34547Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194062O43293Espacenet
EP 4641201 A22025-10-293627O43293Espacenet
JP 2025529142 A2025-09-041215O43293Espacenet
US 12371689 B22025-07-291215O43293Espacenet
JP 2025517969 A2025-06-123627O43293Espacenet
JP 2025517970 A2025-06-124062O43293Espacenet
US 11564998 B22023-01-315206O43293Espacenet
US 11564998 B22023-01-318979O43293Espacenet
US 11446398 B22022-09-2023266O43293Espacenet
US 11446398 B22022-09-2023267O43293Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,435

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDAPK3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant72025
P30CA008748Cancer Center Support Grant52025
P30CA014195Cancer Center Support Grant (CCSG)42025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center42025
P30CA016058Cancer Center Support Grant32025
P40OD018537Bloomington Drosophila Stock Center at Indiana University32025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal32025
R35GM140931Transport, substrate specificity and regulation mechanisms of the ZIP transition metal transporters32025
UL1TR001863Yale Clinical and Translational Science Award32025
P30AG066546South Texas Alzheimer's Disease Center22025

1 to 10 of 1,435Source NIH's project files

See all 1,435 nih grants

Papers1,713

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Zinc Transporter Gene Variants (SLC30A and SLC39A) in Human Disease: From Metal Homeostasis Disruption to Convergent Signaling Pathways.Hum Mutat202642812662PubTator, text miningPubMed
Harnessing the interplay between metal toxicity and DNA methylation in plants.Ecotoxicology202642799936PubTator, text miningPubMed
Multilevel Mechanisms by Which Membrane Transport Proteins Regulate Plant Responses to Heavy Metal Stress: From Ion Perception and Uptake Control to Systemic Signaling and Translational Perspectives.Plant Cell Environ202642782210PubTator, text miningPubMed
Multi-Modal Kinome Profiling Discovers Mesenchymal-Like Polarity Networks that Underly Directed Hepatocellular Carcinoma Cell Migration.bioRxiv202642779861PubTator, text miningPubMed
Symmetry analysis and ancestral sequence reconstruction reveal a symmetrical translocation pathway and activity determinants of ZIP metal transporters.Protein Sci202642747088PubTator, text miningPubMed
Melatonin as a hub signal integrating redox and hormonal crosstalk with multi-omics regulation in plant heavy metal stress tolerance.Plant Physiol Biochem202642731282PubTator, text miningPubMed
The heavy ion-induced up-regulation of ZIP14 is mediated by the PKCNrf2 pathway.Life Sci Space Res (Amst)202642601150PubTator, text miningPubMed
ZIP1 Is a Critical DNA Damage-Responsive Zinc Transporter Induced by Bleomycin via the TNFα-NF-κB Pathway.FASEB J202642599768PubTator, text miningPubMed
Multi-omics analysis reveals the mechanisms of biochar-mediated cadmium transport in Salix: insights into rhizosphere phosphorus-iron coupling and transporter expression.Tree Physiol202642518220PubTator, text miningPubMed
Harnessing biostimulants to alleviate potentially toxic element stress in vegetable crops.Planta202642463972PubTator, text miningPubMed

1 to 10 of 1,713

See all 1,713 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1613

GET https://conductscience.org/api/genes/v1/1613/patents?page=2