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Gene · 1616

DAXX: death domain associated protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DAXX: death domain associated protein. Genes, record 1616. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1616

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Gene

Symbol
DAXX
HGNC
Name
death domain associated protein
HGNC
NCBI Gene ID
1616
NCBI Gene
HGNC ID
HGNC:2681
HGNC
Ensembl
ENSG00000204209
NCBI Gene
Aliases
BING2, DAP6, EAP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UER7Death domain-associated protein 674014Ensembl, GeneID, HGNC

Source UniProt

Patents158

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026219974 A12026-10-222Q9UER7Espacenet
EP 4691494 A12026-02-116Q9UER7Espacenet
JP 2026004568 A2026-01-1443411Q9UER7Espacenet
JP 2026004568 A2026-01-1443412Q9UER7Espacenet
JP 2026004568 A2026-01-1443413Q9UER7Espacenet
JP 2026004568 A2026-01-1443414Q9UER7Espacenet
JP 2026004568 A2026-01-1443421Q9UER7Espacenet
JP 2026004568 A2026-01-1443422Q9UER7Espacenet
JP 2026004568 A2026-01-1443425Q9UER7Espacenet
JP 2026004568 A2026-01-1443429Q9UER7Espacenet

1 to 10 of 158

See all 158 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,149

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDAXX papersNewest fiscal year
P30CA008748Cancer Center Support Grant572025
P30CA010815Consolidated Basic Cancer Research Program342025
P30CA016672Cancer Center Support Grant312025
P30CA006973Regional Oncology Research Center222025
P30CA021765Cancer Center Support Grant (CCSG)172025
P30CA047904Cancer Center Support Grant112025
P30CA014520UW Comprehensive Cancer Center Support92025
P30CA086862Cancer Center Support Grant92025
T32CA009110Training in Areas Fundamental to Cancer Research92025
P30CA006927Comprehensive Cancer Center Program at Fox Chase82025

1 to 10 of 2,149Source NIH's project files

See all 2,149 nih grants

Papers3,633

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exploring Molecular Pathways in Metastasis of Breast Cancer Cells to the Brain: Insights from Gene Expression Analysis and Cellular Origins.J Microsc Ultrastruct202642824931PubTator, text miningPubMed
The Genomic Patterns of Well-Differentiated Pancreatic Neuroendocrine Tumors (NETs) Identify Sub-Sets for Rational Therapeutic Targeting.Int J Mol Sci202642794433PubTator, text miningPubMed
Daxx depletion remodels silent rDNA chromatin and increases UBF-bound transcriptional potential.Biochem Biophys Res Commun202642759275PubTator, text miningPubMed
A comprehensive survey of genetic variants in neuroblastoma.J Genet Eng Biotechnol202642749408PubTator, text miningPubMed
Deconstructing the Alternative Lengthening of Telomeres: Integromics Prioritizes Five Master Hubs Dictating Clinical Survival and Therapeutic Vulnerabilities.Biology (Basel)202642737963PubTator, text miningPubMed
Comprehensive Somatic Profiling of Gastroenteropancreatic Neuroendocrine Neoplasms.Endocr Oncol202642725815PubTator, text miningPubMed
Mast cell leukemia with complex genomic alterations in an elderly patient with prior hematologic and solid malignancies: a case report.Ann Med Surg (Lond)202642724865PubTator, text miningPubMed
Real-World-Feasible Immunohistochemistry of ATRX, DAXX, and Menin Identifies a Subgroup of Non-Functioning Pancreatic Neuroendocrine Tumors with low Recurrence Risk to Guide De-Escalating Surveillance.
Endocr Pathol202642667492PubTator, text miningPubMed
PSIP1::TBL1X: a recurrent gene fusion in pancreatic neuroendocrine tumors.Endocr Relat Cancer202642659417PubTator, text miningPubMed
Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.Nat Neurosci202642608571PubTator, text miningPubMed

1 to 10 of 3,633

See all 3,633 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1616

GET https://conductscience.org/api/genes/v1/1616/patents?page=2