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Gene · 162514

TRPV3: transient receptor potential cation channel subfamily V member 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TRPV3: transient receptor potential cation channel subfamily V member 3. Genes, record 162514. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/162514

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Gene

Symbol
TRPV3
HGNC
Name
transient receptor potential cation channel subfamily V member 3
HGNC
NCBI Gene ID
162514
NCBI Gene
HGNC ID
HGNC:18084
HGNC
Ensembl
ENSG00000167723
NCBI Gene
Aliases
FNEPPK2, OLMS, OLMS1, VRL3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8NET8Transient receptor potential cation channel subfamily V member 379048Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467586Q8NET8Espacenet
JP 2026004568 A2026-01-1467660Q8NET8Espacenet
EP 4641201 A22025-10-2921470Q8NET8Espacenet
JP 2025529142 A2025-09-045078Q8NET8Espacenet
US 12371689 B22025-07-295078Q8NET8Espacenet
JP 2025517969 A2025-06-1221470Q8NET8Espacenet
JP 2025032204 A2025-03-1137741Q8NET8Espacenet
JP 2025004113 A2025-01-141Q8NET8Espacenet
EP 4461818 A22024-11-1337741Q8NET8Espacenet
KR 1020240056847 A2024-05-021Q8NET8Espacenet

1 to 10 of 28

See all 28 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
GRC-15300CHEMBL3707319Transient receptor potential cation channel subfamily V member 3 antagonistANTAGONIST

Source ChEMBL

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants632

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTRPV3 papersNewest fiscal year
R01CA206573Structure and function of Transient Receptor Potential Channels182025
R01NS107253Single-Particle Cryo-EM Characterization of AMPA Receptor Functional States152025
R01AR078814Structural and functional principles of activation and regulation of the transient receptor potential channel TRPV3.92025
R01GM093290Regulation of the epithelial Ca2+ channels TRPV6 and TRPV582025
R01NS070711Nociceptive Mechanisms Underlying Sickle Cell Pain62025
P30EY014800University of Utah Core Vision Research Grant32025
R01EY027920Molecular mechanisms of mechanotransduction in the aqueous outflow pathway32025
ZIANS002945Gating mechanisms and pharmacology of voltage-activated ion channels32025
ZICES103326NIEHS Cryo-EM Core Facility32025
P20GM103466HAWAII INBRE V PROGRAM22025

1 to 10 of 632Source NIH's project files

See all 632 nih grants

Papers1,367

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Targeting epidermal TRPV3 calcium channel alleviates psoriasis-like inflammation in vitro and in vivo.J Invest Dermatol202642785470PubTator, text miningPubMed
Avicularin and Senegenin Suppress TRPV3-Associated TSLP Expression in Human Keratinocytes.Cells202642782759PubTator, text miningPubMed
Pharmacological Activity of Motugivatrep, a Novel Antagonist of Transient Receptor Potential Cation Channel Subfamily V Member 1.Biol Pharm Bull202642749621PubTator, text miningPubMed
Successful Live Birth Following Treatment of Persistent Endometrial Dysbiosis and Recurrent Chronic Endometritis: A Case Report.Reprod Med Biol202642732330PubTator, text miningPubMed
Palmoplantar Keratoderma: A Mechanism-Based Disease Classification.Clin Cosmet Investig Dermatol202642725047PubTator, text miningPubMed
Tape Strip Transcriptomics Reveal Nemolizumab Effects on Pruritus, Hyperplasia, Inflammation, and Extracellular Matrix Markers in Patients With Moderate-to-Severe Atopic Dermatitis.Allergy202642693785PubTator, text miningPubMed
Transient receptor potential vanilloid channels in inflammatory bowel diseases: linking inflammation, angiogenesis, and oxidative stress.Inflammopharmacology202642507268PubTator, text miningPubMed
A non-covalently bound fluorescent probe with a larger fluorescence change for imaging Kv7 channels.Anal Chim Acta202642401463PubTator, text miningPubMed
Large-Scale Cohort Study on the Genetic and Phenotypic Findings of Palmoplantar Keratodermas in the Chinese Population.Exp Dermatol202642384829PubTator, text miningPubMed
Structural diversity of heat-sensing channel TRPV3 with Olmsted syndrome mutations.Nat Commun202642323291PubTator, text miningPubMed

1 to 10 of 1,367

See all 1,367 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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