ConductScience.org, home

Gene · 1629

DBT: dihydrolipoamide branched chain transacylase E2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. DBT: dihydrolipoamide branched chain transacylase E2. Genes, record 1629. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1629

On this page

Gene

Symbol
DBT
HGNC
Name
dihydrolipoamide branched chain transacylase E2
HGNC
NCBI Gene ID
1629
NCBI Gene
HGNC ID
HGNC:2698
HGNC
Ensembl
ENSG00000137992
NCBI Gene
Aliases
BCATE2, BCKAD-E2, BCKADE2, BCKDH-E2, BCOADC-E2, E2, E2B
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P11182Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial4825Ensembl, GeneID, HGNC

Source UniProt

Patents10

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443772P11182Espacenet
EP 4650780 A22025-11-198731P11182Espacenet
EP 4641201 A22025-10-298924P11182Espacenet
JP 2025517969 A2025-06-128924P11182Espacenet
JP 2025517970 A2025-06-128731P11182Espacenet
US 11446398 B22022-09-2024368P11182Espacenet
JP 2022524081 A2022-04-27127339P11182Espacenet
JP 2019054813 A2019-04-11224207P11182Espacenet
JP 2017121241 A2017-07-13224207P11182Espacenet
JP 2015516143 A2015-06-08224207P11182Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants894

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDBT papersNewest fiscal year
R01HL070562Actions of Estrogen on Uterine Artery Endothelium82025
P30CA016672Cancer Center Support Grant72025
R01DK114103Keeping fat out of muscle - Role of Branched Amino AcidsAmino Acids in Insulin Resistance32025
R01EY013124Immunopathogenesis of Adenovirus Keratitis32025
R01HL152446Branched chain amino acids in heart failure32025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025
P30CA014520UW Comprehensive Cancer Center Support22025
P30CA015704Cancer Center Support Grant22025
P30CA091842Cancer Center Support Grant22025
P30CA093373Cancer Center Support Grant P3022025

1 to 10 of 894Source NIH's project files

See all 894 nih grants

Papers1,694

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Development and application of antibody framework region-targeted cross-linking mass spectrometry for epitope screening within patient-derived immune complexes.J Pharm Biomed Anal202742759225PubTator, text miningPubMed
Identification and validation of candidate biomarkers associated with mitochondria and 18 types of programmed cell death in trigeminal neuralgia: insights from transcriptome sequencing.Front Mol Neurosci202642421982PubTator, text miningPubMed
Novel Biomarker for Antimitochondrial Antibodies in Systemic Sclerosis Patients.J Immunol Res202642402832PubTator, text miningPubMed
Analysis of end-stage renal disease mediated by cuproptosis-related genes.Clin Nephrol202642383521PubTator, text miningPubMed
Systematic discovery of pathogen effector functions across human pathogens and pathways.Cell202642379168PubTator, text miningPubMed
Human-centered design of a digital coping intervention for children experiencing post-separation interparental conflict.Ment Health Prev202642221740PubTator, text miningPubMed
A Systematic Bioinformatic Analysis of the miRNA Pathway in Inborn Errors of Amino Acid Metabolism Disorders.Mol Syndromol202642038754PubTator, text miningPubMed
Cuproptosis in spinal cord injury: emerging mechanisms and immunological relevance.Ann Med202641883033PubTator, text miningPubMed
Multilevel associations between skills use, engagement, and treatment outcome in self-guided internet-delivered dialectical behavior therapy for substance use disorders.PLOS Ment Health202641875107PubTator, text miningPubMed
The histone acylation network: emerging therapeutic targets for remodeling the epigenetic landscape in pancreatic ductal adenocarcinoma.Cell Oncol (Dordr)202641874858PubTator, text miningPubMed

1 to 10 of 1,694

See all 1,694 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1629

GET https://conductscience.org/api/genes/v1/1629/grants?page=2