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Gene · 1633

DCK: deoxycytidine kinase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DCK: deoxycytidine kinase. Genes, record 1633. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1633

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Gene

Symbol
DCK
HGNC
Name
deoxycytidine kinase
HGNC
NCBI Gene ID
1633
NCBI Gene
HGNC ID
HGNC:2704
HGNC
Ensembl
ENSG00000156136
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P27707Deoxycytidine kinase26058Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4694917 A12026-02-18580P27707Espacenet
JP 2026004568 A2026-01-1443598P27707Espacenet
EP 4650780 A22025-11-193297P27707Espacenet
EP 4641201 A22025-10-292874P27707Espacenet
JP 2025147176 A2025-10-0616585P27707Espacenet
JP 2025517969 A2025-06-122874P27707Espacenet
JP 2025517970 A2025-06-123297P27707Espacenet
JP 2025028160 A2025-02-2816585P27707Espacenet
KR 1020250010750 A2025-01-2116585P27707Espacenet
JP 2024109657 A2024-08-1416424P27707Espacenet

1 to 10 of 50

See all 50 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,397

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDCK papersNewest fiscal year
P30CA016672Cancer Center Support Grant312025
P30CA021765Cancer Center Support Grant (CCSG)212025
P30CA016042Cancer Center Support Grant192025
P30CA008748Cancer Center Support Grant152025
P30CA043703Case Comprehensive Cancer Center Support Grant112025
R01CA132946Genomics of AML Prognosis102025
P30AI050409Center for AIDS Research at Emory University72025
P30CA006973Regional Oncology Research Center72025
P30CA056036Translational Research in Cancer72025
P30CA168524The University of Kansas Cancer Center62025

1 to 10 of 1,397Source NIH's project files

See all 1,397 nih grants

Papers2,658

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Chromosomal Heterogeneity and Enrichment of Mitotic Regulatory Programs Reveal a Therapeutic Vulnerability in Cytarabine-Resistant FLT3-ITD AML.Curr Issues Mol Biol202642793322PubTator, text miningPubMed
A complex mutational signature generated by cytarabine resistance.NAR Cancer202642630438PubTator, text miningPubMed
Folic acid alleviates neuroinflammation after intracerebral hemorrhage by epigenetically regulating the AMPD2/DCK/NF-κB pathway.Phytomedicine202642542053PubTator, text miningPubMed
Metabolic and Molecular Mechanisms of Gemcitabine Resistance in Urothelial Carcinoma.Cancers (Basel)202642449668PubTator, text miningPubMed
Cellular pharmacology of fludarabine: molecular determinants of transport and metabolism.Front Pharmacol202642239518PubTator, text miningPubMed
Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study.Br J Clin Pharmacol202642220058PubTator, text miningPubMed
Epigenetic Biomarkers for Predicting Nucleoside Analog Drug Response and Resistance in Cancer.Biomolecules202642072708PubTator, text miningPubMed
Marine Bioactive Compounds from Functional Seafoods: Pharmacological Mechanisms and Health Applications.Mar Drugs202641892975PubTator, text miningPubMed
Deoxycytidine kinase inhibition: Rewiring tumor nucleotide metabolism for therapeutic gain.Nucleosides Nucleotides Nucleic Acids202641889017PubTator, text miningPubMed
Research progress of plant-derived chemical compounds for overcoming pancreatic cancer drug resistance.World J Gastroenterol202641810441PubTator, text miningPubMed

1 to 10 of 2,658

See all 2,658 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1633

GET https://conductscience.org/api/genes/v1/1633/patents?page=2