Gene · 1639
DCTN1: dynactin subunit 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DCTN1: dynactin subunit 1. Genes, record 1639. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1639
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14203 | Dynactin subunit 1 | 1,278 | 13 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44379 | Q14203 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7944 | Q14203 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8032 | Q14203 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8032 | Q14203 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7944 | Q14203 | Espacenet |
| US 12258376 B2 | 2025-03-25 | 25 | Q14203 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 132 | Q14203 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 25878 | Q14203 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 128849 | Q14203 | Espacenet |
| JP 2022502411 A | 2022-01-11 | 12 | Q14203 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants900
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DCTN1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 6 | 2025 |
| T32AG000255 | Training in age related neurodegenerative diseases | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| ZIAAG000933 | Genetic etiology of Amyotrophic Lateral Sclerosis | 5 | 2025 |
| I01BX002466 | VA Biorepository Brain Bank | 3 | 2025 |
| P30AG066514 | Mount Sinai Alzheimer's Disease Research Center | 3 | 2025 |
| R01NS120926 | Creating a foundation for personalized age- and sex-based immune-targeted therapies from an ALS longitudinal cohort by identifying peripheral and central immune signatures | 3 | 2025 |
| R37AR027883 | Cell adhesion and tissue dynamics in the skin | 3 | 2025 |
| ZIANS003154 | Genetic characterization of atypical parkinsonism | 3 | 2025 |
1 to 10 of 900Source NIH's project files
See all 900 nih grantsPapers1,366
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| OGT-mediated O-GlcNAcylation of BICD2 drives gemcitabine resistance in pancreatic cancer via accelerating G2/M cell cycle progression. | Drug Resist Updat | 2026 | 42600365 | PubTator, text mining | PubMed |
| The causal role of plasma protein ratios in ulcerative colitis: insights from mendelian randomization and single-cell sequencing. | Open Med (Wars) | 2026 | 42577736 | PubTator, text mining | PubMed |
| Rescuing a refractory Leiomyosarcoma: ALK-DCTN1 fusion as a gateway to long-term control with Ceritinib. | Gynecol Oncol Rep | 2026 | 42569171 | PubTator, text mining | PubMed |
| Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications. | Lancet Neurol | 2026 | 42456684 | PubTator, text mining | PubMed |
| [Rare hereditary and acquired diseases with parkinson's syndrome]. | Fortschr Neurol Psychiatr | 2026 | 42392185 | PubTator, text mining | PubMed |
| p.Ile87Val is a novel conservative DCTN1 variant causing Perry syndrome. | Parkinsonism Relat Disord | 2026 | 41921430 | PubTator, text mining | PubMed |
| Multifactorial anticholinergic toxicity-like presentation and malignant parkinsonism in Perry syndrome. | Parkinsonism Relat Disord | 2026 | 41864034 | PubTator, text mining | PubMed |
| Structural and functional brain asymmetry in relation to heterogeneous causes of situs inversus totalis. | Brain Struct Funct | 2026 | 41824087 | PubTator, text mining | PubMed |
| Short tandem repeat expansions in patients with neurodegenerative dementia. | EBioMedicine | 2026 | 41762523 | PubTator, text mining | PubMed |
| The Development of Novel Treatment Strategies for Rhabdomyosarcoma. | Cancers (Basel) | 2026 | 41749943 | PubTator, text mining | PubMed |
1 to 10 of 1,366
See all 1,366 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1639
GET https://conductscience.org/api/genes/v1/1639/patents?page=2