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HFM1: helicase for meiosis 1

1 protein, 10 patents, 0 drugs, 0 trials, 4,817 NIH grants and 10,110 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHFM1HGNC
Namehelicase for meiosis 1HGNC
NCBI Gene ID164045NCBI Gene
HGNC IDHGNC:20193HGNC
EnsemblENSG00000162669NCBI Gene
AliasesFLJ36760, FLJ39011, HYDM5, MER3, POF9, SEC63D1, Si-11, Si-11-6, helicaseNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
A2PYH4Probable ATP-dependent DNA helicase HFM11,4350Ensembl, GeneID, HGNCUniProt

Patents 10

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-298975A2PYH4Espacenet
JP 2025517969 A2025-06-128975A2PYH4Espacenet
JP 2025024198 A2025-02-1912975A2PYH4Espacenet
US 11446398 B22022-09-2038217A2PYH4Espacenet
JP 2022524081 A2022-04-27141188A2PYH4Espacenet
US 11078247 B22021-08-034958A2PYH4Espacenet
US 9827332 B22017-11-2812975A2PYH4Espacenet
JP 2017121243 A2017-07-1356943A2PYH4Espacenet
US 9254311 B22016-02-0912975A2PYH4Espacenet
JP 2015513912 A2015-05-1856943A2PYH4Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4817

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability682,025NIH's project files
P30CA008748Cancer Center Support Grant422,025NIH's project files
P01CA092584Structural Cell Biology of DNA Repair Machines402,025NIH's project files
ZIAAG000726Function of RecQ helicases in genome stability382,025NIH's project files
ZIAAG000752Model Genetic Systems to Study DNA Repair372,025NIH's project files
ZIAAG000753Fanconi Anemia Pathway352,025NIH's project files
P30CA016672Cancer Center Support Grant222,025NIH's project files
R01ES007061Mechanisms of DNA Double-strand Break End Resection and Repair Pathway Choice142,025NIH's project files
ZIALM000073Comparative Analysis Of Completely Sequenced Genomes142,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)132,025NIH's project files

Papers 10110

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822417PubTator, text miningPubMed
42821439PubTator, text miningPubMed
42812541PubTator, text miningPubMed
42778339PubTator, text miningPubMed
42773178PubTator, text miningPubMed
42755368PubTator, text miningPubMed
42655813PubTator, text miningPubMed
42655645PubTator, text miningPubMed
42629476PubTator, text miningPubMed
42612455PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license