ConductScience.org, home

Library / Genes

DDC: dopa decarboxylase

1 protein, 36 patents, 5 drugs, 122 trials, 1,996 NIH grants and 4,592 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolDDCHGNC
Namedopa decarboxylaseHGNC
NCBI Gene ID1644NCBI Gene
HGNC IDHGNC:2719HGNC
EnsemblENSG00000132437NCBI Gene
AliasesAADCNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P20711Aromatic-L-amino-acid decarboxylase4808Ensembl, GeneID, HGNCUniProt

Patents 36

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4729620 A12026-04-227P20711Espacenet
US 12605467 B22026-04-2131P20711Espacenet
US 12595497 B22026-04-0718P20711Espacenet
WO 2026012952 A12026-01-1546P20711Espacenet
JP 2026004568 A2026-01-1444182P20711Espacenet
JP 2026004568 A2026-01-1444185P20711Espacenet
EP 4641201 A22025-10-297476P20711Espacenet
JP 2025517969 A2025-06-127476P20711Espacenet
JP 2025516136 A2025-05-2731P20711Espacenet
EP 4511482 A12025-02-2631P20711Espacenet

Drugs 5

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BENSERAZIDECHEMBL1096979DOPA decarboxylase inhibitorINHIBITORChEMBL
CARBIDOPACHEMBL1200748DOPA decarboxylase inhibitorINHIBITORChEMBL
CARBIDOPA ANHYDROUSCHEMBL1201236DOPA decarboxylase inhibitorINHIBITORChEMBL
ELADOCAGENE EXUPARVOVECCHEMBL4298189DDC exogenous geneEXOGENOUS GENEChEMBL
FOSCARBIDOPACHEMBL4802240DOPA decarboxylase inhibitorINHIBITORChEMBL

Trials 122

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07267065ELADOCAGENE EXUPARVOVECPHASE1ClinicalTrials.gov
NCT07151378CARBIDOPAPHASE3ClinicalTrials.gov
NCT07138560CARBIDOPAPHASE4ClinicalTrials.gov
NCT06831500CARBIDOPAPHASE1/PHASE2ClinicalTrials.gov
NCT06765668CARBIDOPAPHASE4ClinicalTrials.gov
NCT06729658BENSERAZIDEEARLY_PHASE1ClinicalTrials.gov
NCT06614153CARBIDOPAPHASE2ClinicalTrials.gov
NCT06236230CARBIDOPAPHASE4ClinicalTrials.gov
NCT05781711CARBIDOPAPHASE2ClinicalTrials.gov
NCT05708274CARBIDOPAPHASE1ClinicalTrials.gov

NIH grants 1996

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant62,025NIH's project files
T32CA009054A Training Program for Interdisciplinary Cancer Research52,025NIH's project files
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).52,025NIH's project files
ZIAAA000301Integrative genetics of behavior with high throughput technologies52,025NIH's project files
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)42,025NIH's project files
P30CA016672Cancer Center Support Grant42,025NIH's project files
P40OD018537Bloomington Drosophila Stock Center at Indiana University42,025NIH's project files
P51OD011106Wisconsin National Primate Research Center Support42,025NIH's project files
R01DA007418The Dopamine Synapse and Associative Learning42,025NIH's project files
R01DK114233Studying the Role of the Microenvironment on Differentiation and Maturation of Beta Cells42,025NIH's project files

Papers 4592

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42797415PubTator, text miningPubMed
42779254PubTator, text miningPubMed
42751903PubTator, text miningPubMed
42648782PubTator, text miningPubMed
42567384PubTator, text miningPubMed
42563827PubTator, text miningPubMed
42554773PubTator, text miningPubMed
42547385PubTator, text miningPubMed
42546913PubTator, text miningPubMed
42506398PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license