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TMPRSS6: transmembrane serine protease 6
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Gene · 164656

Papers978

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 978

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TitleJournalYearPMIDFound bySource
Ferritin Normalization Is Not Disease Control in HFE-Related Hemochromatosis: Residual Risk, Transferrin Saturation, and the Hepcidin-Ferroportin Axis.Eur J Haematol202642764193PubTator, text miningPubMed
Deciphering novel targets in salivary gland pleomorphic adenoma by integrating plasma proteomics and parotid transcriptomics analyses.J Dent Sci202642688628PubTator, text miningPubMed
Sapablursen for Erythrocytosis Control in Patients with Polycythemia Vera.Blood202642611791PubTator, text miningPubMed
Are sustainable plant-based diets suitable for all? A nutrigenetic perspective.Nutr Health202642593171PubTator, text miningPubMed
Association of TMPRSS6 gene polymorphisms with severity of iron deficiency anemia in Uzbek schoolchildren: a molecular case-control study.Arch Med Sci202642540599PubTator, text miningPubMed
Hepcidin as a Molecular Hub of Iron Homeostasis: From BMP-SMAD Signaling to Therapeutic Modulation.Biomolecules202642509741PubTator, text miningPubMed
Between scarcity and surfeit: a familial tale of contradictory iron disorders (β -thalassemia and iron-refractory iron deficiency anemia).Ann Hematol202642479051PubTator, text miningPubMed
Correction to 'Targeting the Liver Serine Protease TMPRSS6 Ameliorates Steatosis and Attenuates Fibrosis in Experimental MASLD'.Liver Int202642454756PubTator, text miningPubMed
Aberrant TMPRSS6-Protease Regulation of Disease Mutant HCN4-KCNE1 Channel Complex Depends on the KCNE1-G38S Polymorphism.Arch Pharm (Weinheim)202642424558PubTator, text miningPubMed
Deep Dive into Evolution: How Cetaceans Adapt Their Anticoagulant Genes for Underwater Survival.J Mol Evol202642406052PubTator, text miningPubMed
Functional Iron-Transport Genes-TF and TMPRSS6-As Genetic Determinants of Transferrin and Fasting Glucose in a Kazakh Adult Cohort: A Whole-Exome Sequencing Pilot Study.Int J Mol Sci202642353094PubTator, text miningPubMed
Relationship of Genetic Variability (HIF-1Α (rs11549465; P582S), TMPRSS6 (rs855791; V736A) and ABO (rs651007) and Iron Deficiency in Repeated Blood Donors in 2023: A Cross-Sectional Study Towards Individualized Health Management.
Health Sci Rep202642281581PubTator, text miningPubMed
Phase 2a randomized study to evaluate sapablursen in patients with non-transfusion dependent β-thalassemia intermedia.Blood Adv202642241700PubTator, text miningPubMed
The Genetics of Iron Metabolism on Biochemical and Hematological Phenotypes of Heart Failure.Int J Mol Sci202642123363PubTator, text miningPubMed
Iron: Regulation, redox homeostasis, and ferroptosis in cancer.Ferroptosis Oxid Stress202642099806PubTator, text miningPubMed
A Phase 1 Randomized, Double-Blind, Placebo-Controlled Single and Multiple Ascending Dose Study of DISC-3405, a Novel Recombinant Humanized Monoclonal Antibody Targeting TMPRSS6, in Adult Healthy Volunteers.
J Clin Pharmacol202642053460PubTator, text miningPubMed
Anemia in young women: determinants and artificial intelligence-based management approaches.Front Artif Intell202641799039PubTator, text miningPubMed
Host iron deficiency protects against Plasmodium infection and drives parasite molecular reprofiling.Sci Adv202641758949PubTator, text miningPubMed
Unusual Micronutrient Deficiencies as Causes of Anemia.Nutrients202641754181PubTator, text miningPubMed
TF-rs1049296 C>T Variant Modifies the Association between Hepatic Iron Stores and Liver Fibrosis in Metabolic Dysfunction-associated Steatotic Liver Disease.J Clin Transl Hepatol202641659995PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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