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GADD45A: growth arrest and DNA damage inducible alpha

1 protein, 62 patents, 0 drugs, 0 trials, 3,489 NIH grants and 6,330 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGADD45AHGNC
Namegrowth arrest and DNA damage inducible alphaHGNC
NCBI Gene ID1647NCBI Gene
HGNC IDHGNC:4095HGNC
EnsemblENSG00000116717NCBI Gene
AliasesDDIT1, GADD45NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P24522Growth arrest and DNA damage-inducible protein GADD45 alpha1651Ensembl, GeneID, HGNCUniProt

Patents 62

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4805378 A12026-09-16687P24522Espacenet
EP 4650780 A22025-11-198875P24522Espacenet
EP 4641202 A22025-10-295504P24522Espacenet
JP 2025517970 A2025-06-128875P24522Espacenet
JP 2025032204 A2025-03-1128805P24522Espacenet
KR 1020250017231 A2025-02-045504P24522Espacenet
EP 4461818 A22024-11-1328805P24522Espacenet
JP 2024123008 A2024-09-106379P24522Espacenet
JP 2024507735 A2024-02-21138P24522Espacenet
US 11708396 B22023-07-252220P24522Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3489

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant362,025NIH's project files
P30ES006694Southwest Environmental Health Sciences Center172,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant152,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant142,025NIH's project files
P30CA008748Cancer Center Support Grant102,025NIH's project files
P30CA016087Cancer Center Support Grant92,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase82,025NIH's project files
P30CA016058Cancer Center Support Grant82,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202882,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant82,025NIH's project files

Papers 6330

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821135PubTator, text miningPubMed
42744597PubTator, text miningPubMed
42691609PubTator, text miningPubMed
42681921PubTator, text miningPubMed
42651847PubTator, text miningPubMed
42643032PubTator, text miningPubMed
42636425PubTator, text miningPubMed
42633148PubTator, text miningPubMed
42579704PubTator, text miningPubMed
42566833PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license