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Gene · 1650

DDOST: dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DDOST: dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit. Genes, record 1650. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1650

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Gene

Symbol
DDOST
HGNC
Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
HGNC
NCBI Gene ID
1650
NCBI Gene
HGNC ID
HGNC:2728
HGNC
Ensembl
ENSG00000244038
NCBI Gene
Aliases
AGER1, CDG1R, GATD6, KIAA0115, OKSWcl45, OST, OST48, WBP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P39656Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit4566Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21244P39656Espacenet
JP 2026004568 A2026-01-1444159P39656Espacenet
EP 4650780 A22025-11-199564P39656Espacenet
JP 2025147176 A2025-10-064021P39656Espacenet
JP 2025147176 A2025-10-064022P39656Espacenet
JP 2025529142 A2025-09-041232P39656Espacenet
JP 2025529142 A2025-09-046120P39656Espacenet
US 12371689 B22025-07-291232P39656Espacenet
US 12371689 B22025-07-296120P39656Espacenet
JP 2025517970 A2025-06-129564P39656Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants950

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDDOST papersNewest fiscal year
R01GM039334Deciphering the Principles of Membrane-Associated Glycan Assembly for Glycoconjugate Biosynthesis172025
R01DK099551New Congenital Disorders of Glycosylation: Therapy and Models132025
R35GM133552Coordination of chaperone interactions that dictate protein folding and trafficking62025
R01GM086874Cellular protein maturation and degradation52025
P30CA062203Cancer Center Support Grant42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA016672Cancer Center Support Grant32025
P30DK034989Yale Liver Center32025
P30ES001247Environmental Agents as Modulators of Disease Processes32025
R24GM137782National Glycoscience Resource- CCRC Service and Training - NGlycoR@CCRC32025

1 to 10 of 950Source NIH's project files

See all 950 nih grants

Papers1,417

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
STT3 promotes cervical cancer proliferation and apoptosis via PI3K/AKT pathway.Transl Oncol202642636657PubTator, text miningPubMed
Omega-3 fatty acids as modulators of advanced glycation end products in aging: mechanistic pathways and clinical implications - a narrative review.Front Aging202642523776PubTator, text miningPubMed
DDOST mediates cervical cancer cell malignant progression by interacting with SMARCA4.Am J Cancer Res202642465022PubTator, text miningPubMed
TUSC3 serves as a rate-limiting gatekeeper of a glycan-mediated ER triage checkpoint for BMP4/Dpp.Cell Rep202642378087PubTator, text miningPubMed
Isoform-dependent glycosylation of respiratory viral class I fusion glycoproteins by oligosaccharyltransferases.Virology202641962458PubTator, text miningPubMed
A homozygous nonsense variant in the oligosaccharyltransferase complex gene, RPN1, causes a congenital disorder of glycosylation.HGG Adv202641935956PubTator, text miningPubMed
HAMMER: hairpin-based APOBEC3A-mediated mRNA editing reporter.Nucleic Acids Res202641925228PubTator, text miningPubMed
Spatiotemporal regulation of N-glycosylation in the endoplasmic reticulum of mammalian cells.Biochim Biophys Acta Gen Subj202641895537PubTator, text miningPubMed
Glycosylation as a dynamic regulator of RLR and cGAS-STING innate immune signalling pathways.Commun Biol202641876639PubTator, text miningPubMed
Calsyntenin-3 suppresses inflammation via inhibition of TLR N-glycosylation and membrane localization.Proc Natl Acad Sci U S A202641849401PubTator, text miningPubMed

1 to 10 of 1,417

See all 1,417 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1650

GET https://conductscience.org/api/genes/v1/1650/patents?page=2