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Gene · 1660

DHX9: DExH-box helicase 9

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DHX9: DExH-box helicase 9. Genes, record 1660. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1660

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Gene

Symbol
DHX9
HGNC
Name
DExH-box helicase 9
HGNC
NCBI Gene ID
1660
NCBI Gene
HGNC ID
HGNC:2750
HGNC
Ensembl
ENSG00000135829
NCBI Gene
Aliases
DDX9, LKP, MRD75, NDH2, NDHII, RHA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q08211ATP-dependent RNA helicase A1,2706Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443394Q08211Espacenet
WO 2025252547 A12025-12-1134Q08211Espacenet
EP 4660322 A12025-12-1034Q08211Espacenet
EP 4650780 A22025-11-198249Q08211Espacenet
EP 4641201 A22025-10-298430Q08211Espacenet
JP 2025517969 A2025-06-128430Q08211Espacenet
JP 2025517970 A2025-06-128249Q08211Espacenet
WO 2025016918 A12025-01-2334Q08211Espacenet
EP 4495265 A12025-01-2234Q08211Espacenet
EP 4357462 A12024-04-2434Q08211Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,678

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDHX9 papersNewest fiscal year
P30CA016672Cancer Center Support Grant132025
P01CA100730Retrovirus Models of Cancer122025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant112025
P30CA008748Cancer Center Support Grant102025
P30CA016086Cancer Center Support Grant102025
P30CA016058Cancer Center Support Grant82025
R01AI080607Studies in Poxvirus Host Range Genes and Tropism82025
P30CA015704Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
P30CA022453CANCER CENTER SUPPORT GRANT42025

1 to 10 of 1,678Source NIH's project files

See all 1,678 nih grants

Papers2,696

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The phage shock protein A (PspA) maintains membrane potential and supports NADH dehydrogenase function in mycobacteria.bioRxiv202642818691PubTator, text miningPubMed
GSLR Drives Lung Adenocarcinoma as a Critical Regulator of Energy Homeostasis Through Creatine Kinase B Activation.Adv Sci (Weinh)202642801620PubTator, text miningPubMed
Resolution of viral R-loop by DHX9 promotes hepatitis B virus replication.mBio202642757849PubTator, text miningPubMed
A novel positive feedback regulatory loop, TGF-β1/SMAD4/miR-184, controls the follicular development in sows.Zool Res202642706794PubTator, text miningPubMed
Mutated p53 results in altered type I interferon pathway expression and signaling in endometrial cancer.Gynecol Oncol202642705125PubTator, text miningPubMed
Integrated LiP-MS and quantitative proteomics reveal coordinated alterations in protein conformation and expression across tumor and peritumoral regions in hepatocellular carcinoma.Sci Rep202642686792PubTator, text miningPubMed
The evolution and mechanistic versatility of the bacterial NADH dehydrogenases type II.FEBS J202642642942PubTator, text miningPubMed
R-loops in colorectal cancer: mechanisms, mapping strategies, and therapeutic opportunities.Mol Biol Rep202642593691PubTator, text miningPubMed
Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9-mediated R-loop resolution.Imeta202642504169PubTator, text miningPubMed
Context-dependent roles of DHX9 in Cancer: Molecular mechanisms, biomarker potential, and therapeutic perspectives.Biochim Biophys Acta Rev Cancer202642492626PubTator, text miningPubMed

1 to 10 of 2,696

See all 2,696 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1660

GET https://conductscience.org/api/genes/v1/1660/patents?page=2