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Gene · 1673

DEFB4A: defensin beta 4A

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. DEFB4A: defensin beta 4A. Genes, record 1673. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/1673

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
DEFB4A
HGNC
Name
defensin beta 4A
HGNC
NCBI Gene ID
1673
NCBI Gene
HGNC ID
HGNC:2767
HGNC
Ensembl
ENSG00000171711
NCBI Gene
Aliases
BD-2, DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15263Defensin beta 4A646Ensembl, GeneID, HGNC

Source UniProt

Patents122

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1914808O15263Espacenet
EP 4650780 A22025-11-194221O15263Espacenet
JP 2025169942 A2025-11-14944O15263Espacenet
JP 2025169942 A2025-11-14945O15263Espacenet
JP 2025147176 A2025-10-064167O15263Espacenet
JP 2025147176 A2025-10-064168O15263Espacenet
US 12409247 B22025-09-0985O15263Espacenet
JP 2025529142 A2025-09-046168O15263Espacenet
JP 2025529142 A2025-09-046169O15263Espacenet
US 12371689 B22025-07-296168O15263Espacenet

1 to 10 of 122

See all 122 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,073

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA023108Cancer Center Support Grant142025
R01AI022553Molecular Analysis of Host Immune Response in Leprosy142025
R01AR040312CD1-restricted T-cell Responses in Skin142025
P30EY007551Center Core Grant for Vision Research122025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success92025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center82025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202882025
P30AI036219Rustbelt Center for AIDS Research (Case/UHC-Pitt CFAR)72025
P30CA016672Cancer Center Support Grant72025
R37DE022550Host and Fungal Regulation of Type 17 Immunity to Oral Candidiasis72025

1 to 10 of 2,073Source NIH's project files

See all 2,073 nih grants

Papers4,248

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42798998PubTator, text miningPubMed
42725278PubTator, text miningPubMed
42693835PubTator, text miningPubMed
42687878PubTator, text miningPubMed
42619710PubTator, text miningPubMed
42598629PubTator, text miningPubMed
42590198PubTator, text miningPubMed
42582268PubTator, text miningPubMed
42580156PubTator, text miningPubMed
42561958PubTator, text miningPubMed

1 to 10 of 4,248

See all 4,248 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1673

GET https://conductscience.org/api/genes/v1/1673/patents?page=2